选择性穿皮冠状动脉干预患者的对比诱导性脏病预防的不同水化方法:一项回顾性研究
Fei Chen1, Jingchao Lu1, Xiuchun Yang1
1Department of Cardiology, the Second Hospital of Hebei Medical University and the Institute of Cardiocerebrovascular Disease of Hebei Province, Shijiazhuang, 050000, China.
BMC cardiovascular disorders
|June 24, 2023
概括
在接受皮肤穿透冠状动脉干预 (PCI) 的患者中,术后水化与术前水化同样有效预防对比诱导性病 (CIN). 这一发现支持心脏手术中两种水化策略的安全性和有效性相似.
科学领域:
- 心脏病学 心脏病学
- 腎臟病學 (nephrology) 是一種醫學.
- 放射学 放射学是一门学科.
背景情况:
- 对比诱导性病 (CIN) 是心脏手术后的一个重大问题.
- 补水是预防CIN的主要方法.
- 水的最佳时间 (手术前与手术后) 仍在争论中.
研究的目的:
- 为了比较程序前与程序后水化在预防CIN的有效性.
- 评估在接受选择性皮肤冠状动脉干预 (PCI) 的患者中CIN发生率和不良事件.
主要方法:
- 追溯研究与倾向性得分匹配.
- 198个程序后水化病例与396个程序前水化病例的比较.
- 在PCI后的48小时内分析CIN发病率和PCI后30天内主要不良事件.
主要成果:
- 在术后组中,CIN的发病率为3.54%,在术前组为4.8% (p = 0.478),没有显著差异.
- 主要不良事件在各组之间是相似的 (3.03%对2.02%,p = 0.830).
- 对CIN的独立风险因素包括糖尿病,基线BNP和cystatin C,以及对比剂剂量.
结论:
- 在选择性PCI中,术后补水是治疗前补水的有效替代方案,用于预防CIN.
- 这两种水化策略都显示出可比的疗效和安全性.
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