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Updated: Jul 25, 2025

Nucleocapsid Annealing-Mediated Electrophoresis NAME Assay Allows the Rapid Identification of HIV-1 Nucleocapsid Inhibitors
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艾滋病毒-1囊核是一个机会主义的核导入受体

Guangai Xue1, Hyun Jae Yu2, Cindy Buffone3

  • 1Model Development Section, Cancer Innovation Laboratory, National Cancer Institute, Frederick, MD, 21702, USA.

Nature communications
|June 24, 2023
PubMed
概括

人类免疫缺陷病毒1型 (HIV-1) 的核入口依赖于其囊体 (CA) 与特定的核毛孔复合蛋白 (Nups) 相互作用. 这些相互作用是由宿主因子 (如环素A) 调节的,揭示了HIV-1的存在.

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