在COVID后患者中未被怀疑的亚临床左心室功能障碍:现实世界的观察
Parthasarathi Bhattacharyya1, Sayoni Sengupta2, Aniruddha De3
1Consultant Pulmonologist.
The Journal of the Association of Physicians of India
|June 25, 2023
概括
在COVID-19后患有肺部问题的患者中,亚临床心肌功能障碍可能会持续存在. 心声扫描显示这些人左心室全球纵向应变 (LVGLS) 损伤,表明潜在的长期心脏影响.
科学领域:
- 心脏病学 心脏病学
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
背景情况:
- 亚临床心肌功能障碍是COVID-19后患者潜在的长期并发症.
- 在COVID-19后显著的肺部参与可能与心脏变化有关.
研究的目的:
- 在长期COVID-19患者中评估亚临床心肌功能障碍,有显著的肺部参与.
- 评估心脏功能使用心声回声学,包括全球纵向应变,与肺状况和住院病史相关.
主要方法:
- 左心室 (LV) 和右心室 (RV) 全球纵向应变的心声评估.
- 螺旋测量和COPD评估测试 (CAT) 的得分测量.
- 在双椅子测试 (2CT) 期间,回顾性评分急性阶段症状和评估脉率变化.
主要成果:
- 非住院患者的症状得分较高,但随访时肺功能 (FEV1,CAT得分) 和心脏功能 (TAPSE,LVGLS) 更好.
- 左心室全球纵向应变 (LVGLS) 在有住院病史的患者中显著受损.
- 多变量分析表明,2CT中的LVGLS和最大脉率差异是区分组的关键因素.
结论:
- 亚临床心肌功能障碍可能会在COVID-19后的患者中持续存在,即使没有先前的心脏问题,肺部也会受到重大影响.
- 这些患者在2CT中观察到较高的最大脉冲率差异.
- 需要进一步调查,以了解COVID-19的长期心脏影响.
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