系统性硬化症的皮肤特征,自身抗体概况和指甲毛细分镜:对60例病例的研究
Jayati Dave1, Sunanda Mahajan2, Prasad Khadilkar3
1Bonded Assistant Professor;Corresponding Author.
The Journal of the Association of Physicians of India
|June 25, 2023
概括
系统性硬化症 (SSc) 诊断得到早期皮肤发现的帮助,改性罗丹南.
科学领域:
- 类风湿病学 类风湿病学
- 皮肤病学 皮肤病学
- 免疫学 免疫学 免疫学
背景情况:
- 系统性硬化症 (SSc) 是一种慢性自身免疫性疾病,具有多样化的皮肤表现,通常作为初始指标.
- 早期识别皮肤症状对于及时诊断和管理可能严重的全身并发症至关重要.
研究的目的:
- 调查西印度SSc患者的临床特征.
- 评估修改后的罗丹皮肤评分 (mRSS) 和指甲毛囊镜 (NFC) 在SSc.中的实用性.
- 为了将抗体配置文件与SSc.中的特定皮肤表现相关联.
主要方法:
- 60名SSc患者 (2017-2018) 的评估符合EULAR 2013分类标准.
- 数据收集包括人口统计,皮肤特征,自身抗体概况,mRSS和NFC模式.
主要成果:
- 雷诺病现象 (95%) 和皮肤收紧 (90%) 是最常见的症状.
- 常见的皮肤检查发现包括硬化 (86.7%),星形痕 (78.3%),和鼻 (76.7%).
- 在59名患者中,抗核抗体 (ANA) 呈阳性,在49名患者中,抗毒素酶抗体 (ATA) 呈阳性,在7名患者中,抗中心体抗体 (ACA) 呈阳性.
结论:
- 这项研究强调了早期皮肤检测在SSc诊断中的重要性.
- 修改后的罗丹皮肤评分 (mRSS) 和指甲毛细透视 (NFC) 是SSc评估的宝贵工具.
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