在第三级护理医院的系统性狼患者中肺部参与

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Dibyayanam Sahu¹, Sandip Saha², Sharmistha Bhattacherjee³

¹Senior Resident, Department of Neurology, Bangur Institute of Neurology, Kolkata.

The Journal of the Association of Physicians of India

|June 25, 2023

概括

在全身性红斑狼 (SLE) 中,肺部的参与是常见的,咳和肺部溢出是常见的. 这项研究强调了SLE患者肺部问题的严重流行,强调了对这些表现更加关注的必要性.

科学领域:

类风湿病学类风湿病学
肺部病理学肺部病理学
内部医学内部医学

背景情况:

系统性红斑狼 (SLE) 经常导致肺部感染,但与脏,中枢神经系统或皮肤问题相比,研究往往忽略了这些表现.
肺部并发症是SLE发病率和死亡率的一个重要,但往往被低估的方面.

研究的目的:

确定诊断为SLE的患者肺部感染的患病率和模式.
评估SLE患者在第三级护理环境中的呼吸系统症状和放射性发现的范围.

主要方法:

一项横截面观察性研究涉及70名被诊断为SLE患者,符合ACR标准.
数据收集包括临床检查,呼吸和心血管评估,以及胸部X射线,PFT,心声和HRCT/CT扫描等调查.

主要成果:

大多数参与者是年轻的女性 (21-30岁);大多数是未经治疗过的.
咳是最常见的呈现症状. 胸部X射线在37%的患者中显示出胸腔病理,PFT在4.3%的患者中显示出限制性模式,心声回声显示了19.6%的肺动脉高血压.
在19.4%的患者中,HRCT发现了间歇性肺部疾病 (ILD),在研究队列中,肺部参与的总体患病率为67%.

结论:

在SLE中,肺部表现,包括咳和胸腔溢液,很普遍,有助于患者的发病率.
该研究发现肺部感染的患病率很高 (67%),ILD和肺部疾病是显著的发现.
建议进行进一步的纵向研究,以将疾病活性与SLE早期肺部参与相关联.

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