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Updated: Jul 25, 2025

Preparation of Single-Cell Suspension of Mouse Thymic Epithelial Cells and Staining of Intracellular Molecules for Flow Cytometric AnalysisMechanisms
09:41

Preparation of Single-Cell Suspension of Mouse Thymic Epithelial Cells and Staining of Intracellular Molecules for Flow Cytometric AnalysisMechanisms

Published on: July 26, 2024

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胸膜上皮质细胞上的布罗菲林2a2 (Btn2a2) 表达促进了中央T细胞的耐受性,并预防了自身免疫性疾病

Michael Frech1, Heike Danzer1, Pooja Uchil1

  • 1Department of Internal Medicine 3, Rheumatology and Immunology, Friedrich-Alexander-Universiät Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany; Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany.

Journal of autoimmunity
|June 25, 2023
PubMed
概括

布蒂罗菲林2a2 (Btn2a2),主要来自胸膜上皮细胞,对于T细胞耐受性至关重要. 在小鼠中缺少它会导致类似于Sjögren的自身免疫.

关键词:
自身免疫性疾病是一种自身免疫性疾病.这是一种自身免疫力.布蒂罗菲林2a2 (Btn2a2) 是一种中心的宽容度是中央的宽容度.主要的Sjögren综合征 (pSS) 是一个主要的疾病.甲状腺上皮细胞 (TEC)

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