植入大动脉或心脉位置的生物门的耐用性:全国范围的队列研究
Chun-Yu Chen1, Chia-Pin Lin2, Kuo-Chun Hung2
1Department of Anesthesiology, Chang Gung Memorial Hospital, Linkou Medical Center, Chang Gung University, Taoyuan City, Taiwan; Department of Medicine, College of Medicine, Chang Gung University, Taoyuan City, Taiwan.
The Annals of thoracic surgery
|June 25, 2023
概括
生物假体大动脉置换提供了比米特拉置换更好的长期耐用性和存活率. 这一发现凸显了改善生物假体门干预措施的必要性,以扩大其在心脏手术中的使用.
科学领域:
- 心血管外科心血管外科
- 生物材料科学 生物材料科学
- 临床结果研究研究
背景情况:
- 生物假体门越来越多地用于大动脉和心心门的更换.
- 有限的基于人群的研究存在于这些门的长期耐用性.
研究的目的:
- 为了评估和比较生物假体门的长期耐用性,在米特拉和大动脉位置.
- 评估与生物假体门置换相关的重新手术率和全因死亡率.
主要方法:
- 利用台湾国家健康保险研究数据库 (2001-2017).
- 使用倾向性得分匹配 (1:1比率) 对比米特拉与大动脉位置的生物门耐用性.
- 重新手术是主要结果;全因死亡也被分析.
主要成果:
- 大动脉置换 (AVR) 的重复手术发生率较低 (2.6%),而米特拉置换 (MVR) 的发生率较低 (3.5% (HR 1.41).
- 与AVR (32.6%) (HR 1.21) 相比,MVR队列具有更高的全因死亡风险 (36.5%).
- 位于大动脉位置的门在双门更换中不太可能需要重新植入.
结论:
- 生物假体大动脉的放置证明了优越的耐用性和降低长期死亡率.
- 提高生物假体门的耐用性对于扩大它们在门更换程序中的应用至关重要.
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