通过阴道分娩后的数量和计算产后血损失的比较
Hugo Madar1, Loïc Sentilhes1, François Goffinet2
1Department of Obstetrics and Gynecology, Bordeaux University Hospital, Bordeaux, France (Drs Madar and Sentilhes).
American journal of obstetrics & gynecology MFM
|June 25, 2023
概括
在产后出血评估中,量化血液损失测量低于计算血液损失. 这种差异随着血液损失的增加而增加,影响了产后出血的临床解释.
科学领域:
- 产科和妇科 产科和妇科
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 临床研究 临床研究
背景情况:
- 在产后血液损失评估方法上缺乏共识,这挑战了文献的可比性.
- 使用体积技术的定量失血 (QBL) 有局限性,包括主观性和潜在偏差.
- 基于实验室参数的计算血液损失 (CBL) 提供了一个客观的方法,但需要进一步与QBL进行比较.
研究的目的:
- 用定量和计算方法比较阴道分娩后产后流血的分布.
- 根据每个评估方法来评估异常产后血流的发生率.
主要方法:
- 来自3个多中心随机对照试验的数据分析,涉及8341名阴道分娩后的个人.
- 量化血液损失用分级收集袋测量;计算的血液损失来源于周周部分血红素的变化.
- 多项式回归和斯皮尔曼相关性用于建模QBL和CBL之间的关联.
主要成果:
- 中位数QBL (100毫升) 显著低于中位数CBL (260毫升).
- 与CBL (32.3%) 相比,QBL (9.6%) 的异常血流 (≥500毫升) 的发生率明显较低.
- QBL和CBL显示出显著但中度的相关性 (斯皮尔曼系数=0.44),在较高的失血量时差异越来越大.
结论:
- 在阴道分娩后,定量和计算的血液损失有中等的相关性,但不能互换.
- 临床医生必须认识到,QBL始终低于CBL,随着血液损失的增加,差异会扩大.
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