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相关概念视频

Obesity01:24

Obesity

549
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
549
Carbohydrate Metabolism01:36

Carbohydrate Metabolism

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Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
11.3K
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

1.0K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
1.0K
Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

605
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
605
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

2.6K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.6K
Psychoneuroimmunology: Diabetes and Cancer01:19

Psychoneuroimmunology: Diabetes and Cancer

49
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
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相关实验视频

Updated: Jul 25, 2025

Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes
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Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes

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肥胖和糖尿病的疾病

Chrysoula Boutari1, Antea DeMarsilis2, Christos S Mantzoros3

  • 1Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Hippokration General Hospital, Thessaloniki, Greece; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

Diabetes research and clinical practice
|June 25, 2023
PubMed
概括

肥胖和2型糖尿病 (T2DM) 的共享机制,影响炎症和内分泌功能. 管理肥胖症可以改善T2DM,心血管疾病和NAFLD等相关疾病.

科学领域:

  • 内分泌学和代谢性疾病.
  • 慢性病的病理生理学 慢性病的病理生理学
关键词:
抗糖尿病药物 抗糖尿病药物心血管疾病是什么心血管疾病糖尿病是一种糖尿病.非酒精性脂肪性肝病是非酒精性脂肪性肝病.肥胖问题 肥胖问题在T2DM管理方面,我们有很多问题.

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An Advanced Murine Model for Nonalcoholic Steatohepatitis in Association with Type 2 Diabetes
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An Advanced Murine Model for Nonalcoholic Steatohepatitis in Association with Type 2 Diabetes

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Study of In Vivo Glucose Metabolism in High-fat Diet-fed Mice Using Oral Glucose Tolerance Test OGTT and Insulin Tolerance Test ITT
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相关实验视频

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Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes

Published on: March 7, 2025

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An Advanced Murine Model for Nonalcoholic Steatohepatitis in Association with Type 2 Diabetes
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An Advanced Murine Model for Nonalcoholic Steatohepatitis in Association with Type 2 Diabetes

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背景情况:

  • 肥胖是一种全球流行病,经常与2型糖尿病 (T2DM) 一起发生.
  • 共享的病理生理路径将肥胖和T2DM联系起来,包括炎症,脂肪组织的内分泌功能障碍和线粒体问题.
  • 与肥胖相关的疾病,如心血管疾病 (CVD) 和非酒精性脂肪肝疾病 (NAFLD) 分享这些病理生理联系.

结论:

  • 肥胖和T2DM是相互关联的代谢障碍,具有重叠的病理生理特征.
  • 了解这些共享机制对于有效的临床管理至关重要.
  • 针对肥胖的综合治疗方法对于改善T2DM和相关疾病的结果至关重要.