肥胖和糖尿病的疾病
Chrysoula Boutari1, Antea DeMarsilis2, Christos S Mantzoros3
1Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Hippokration General Hospital, Thessaloniki, Greece; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
肥胖和2型糖尿病 (T2DM) 的共享机制,影响炎症和内分泌功能. 管理肥胖症可以改善T2DM,心血管疾病和NAFLD等相关疾病.
科学领域:
- 内分泌学和代谢性疾病.
- 慢性病的病理生理学 慢性病的病理生理学
背景情况:
- 肥胖是一种全球流行病,经常与2型糖尿病 (T2DM) 一起发生.
- 共享的病理生理路径将肥胖和T2DM联系起来,包括炎症,脂肪组织的内分泌功能障碍和线粒体问题.
- 与肥胖相关的疾病,如心血管疾病 (CVD) 和非酒精性脂肪肝疾病 (NAFLD) 分享这些病理生理联系.
结论:
- 肥胖和T2DM是相互关联的代谢障碍,具有重叠的病理生理特征.
- 了解这些共享机制对于有效的临床管理至关重要.
- 针对肥胖的综合治疗方法对于改善T2DM和相关疾病的结果至关重要.
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