使用便培养物作为减少儿科重症监护病房 (PICU) 中CRE感染的方法,对抗卡巴因的肠道细菌 (CRE) 进行积极监测
Ravi Kumar Krupanandan1, Sudeep Kumar Kapalavai1, Alok Shimee Ekka2
1Department of Pediatric Critical Care, Kanchi Kamakoti CHILDS Trust Hospital, Chennai, India.
Indian journal of medical microbiology
|June 25, 2023
概括
对抗卡巴胺耐药肠道细菌 (CRE) 的积极监测显著减少了儿科重症监护室 (PICU) 中的CRE殖民和感染. 这一策略对于在替代抗生素有限的情况下管理CRE传播至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 临界护理医学 临界护理医学
- 微生物学 微生物学
背景情况:
- 耐卡巴胺 Enterobacteriaceae (CRE) 感染是一个日益严重的全球健康问题.
- 有限的替代抗生素需要有效的感染传播预防策略.
- 通过积极监测及早检测是管理CRE的关键.
研究的目的:
- 评估积极CRE监测对儿科重症监护室 (PICU) 中感染率的影响.
主要方法:
- 从2013年7月到2015年6月,在一个有10个病床的PICU中进行了一项回顾性观察研究.
- 在大多数PICU患者中,收集了直肠拭子用于CRE查.
- 对患者进行接触隔离,对CRE检测呈阳性.
主要成果:
- 在1022名患者中,分析了1262个直肠拭子,显示了19.5%的CRE殖民率.
- 在干预后,ICU获得的CRE殖民化减少了36%.
- 观察到ICU获得的CRE感染减少了100%,两者都具有统计学意义 (p < 0.0001).
结论:
- 积极的CRE监测与有针对性的接触隔离相结合,有效地降低了PICU中的CRE殖民和感染率.
- 这种方法对于控制重症监护机构中CRE传播至关重要.
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