相关实验视频

Updated: Jul 25, 2025

A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy PRRT: 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods

A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy PRRT: 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods

Published on: April 24, 2020

PSMA PET/CT用于对Lu-PSMA疗法的反应评估177

Philipp E Hartrampf¹, Sebastian E Serfling¹, Kerstin Michalski¹

¹Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.

Seminars in nuclear medicine

|June 25, 2023

概括

前列腺特异性膜抗原 (PSMA) PET/CT对于前列腺癌 (PCa) 管理至关重要. 本综述研究了其在监测治疗反应中的作用,特别是针对PSMA向放射性干疗法 (RLT),并比较了新的反应标准.

科学领域:

在瘤学瘤学.
核医学是一种核医学.
放射学放射学是一门学科.

背景情况:

前列腺特异性膜抗原 (PSMA) PET/CT是前列腺癌 (PCa) 管理的组成部分,特别是生化复发和分期.
它的使用正在扩大,用于识别PSMA向放射性干疗法 (RLT) 的候选人.
目前的响应监测主要依赖于传统的成像方式.

研究的目的:

审查PSMA PET/CT目前的状态,以监测PCa中的治疗反应.
专注于对接受PSMA向放射性干疗法 (RLT) 患者的反应评估.
为了比较最近开发的PSMA PET/CT的反应标准.

主要方法:

对PSMA PET/CT用于PCa中响应监测的研究的文献综述.
专注于使用[177Lu]Lu标记的PSMA联体剂进行PSMA向性放射性联体疗法 (RLT).
建立和新兴的PSMA PET/CT反应标准的对比比较.

主要成果:

在PCa中,PSMA PET/CT越来越多地用于响应评估,超越了传统的成像.
包括"PSMA PET进展标准"和"RECIP 1.0"在内的各种标准正在出现,用于定义疾病进展.
对这些标准进行比较分析对于标准化响应评估至关重要.

结论:

在PCa中,PSMA PET/CT提供了一个分子成像方法来监测PCa的反应,补充了传统方法.
需要标准化的标准来准确评估治疗疗效,特别是PSMA-RLT.
进一步验证PSMA PET/CT反应标准对于临床实施至关重要.

更多相关视频

Radiosynthesis, Quality Control, and Small Animal Positron Emission Tomography Imaging of 68Ga-Labelled Nano Molecules

Radiosynthesis, Quality Control, and Small Animal Positron Emission Tomography Imaging of ⁶⁸Ga-Labelled Nano Molecules

Published on: October 4, 2024

Development of a 68Gallium-Labeled D-Peptide PET Tracer for Imaging Programmed Death-Ligand 1 Expression

Development of a 68Gallium-Labeled D-Peptide PET Tracer for Imaging Programmed Death-Ligand 1 Expression

Published on: February 3, 2023

相关概念视频

Positron Emission Tomography

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...