整体儿科瘤学:迈向第二次哥白尼革命
Nicolas André1, Marie Castets2, Eddy Pasquier3
1Service d'Hématologie et Oncologie Pédiatrique, Timone Hospital, AP-HM, Marseille, France; Reverse Molecular Pharmacology in Pediatric Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Aix-Marseille Université, CNRS, INSERM, Institut Paoli Calmettes, Marseille, France; Metronomics Global Health Initiative, Marseille, France.
Trends in cancer
|June 25, 2023
概括
对瘤学的全新整体方法,考虑整个身体,与儿科癌症有关. 这种方法需要特别考虑治疗患有癌症的儿童.
科学领域:
- 在瘤学瘤学.
- 儿科瘤学 儿科瘤学
- 系统生物学 系统生物学
背景情况:
- 已经提出了一种对瘤学的整体方法.
- 这种方法整合了对癌症的原因和进展的全身理解.
- 它还包括开发新的治疗策略.
研究的目的:
- 讨论一个整体瘤学方法在儿科瘤学中的相关性.
- 在这个框架内突出儿童癌症护理所需的具体考虑.
主要方法:
- 概念讨论和文献评论.
- 将系统生物学原理纳入儿科瘤学.
- 对现有的儿科癌症治疗模式的分析.
主要成果:
- 整体瘤学概念适用于儿科癌症.
- 儿童的特定生物学和发育因素需要量身定制的方法.
- 对孩子的整个系统的全面了解对于有效的治疗至关重要.
结论:
- 对瘤学的全身综合方法对儿科癌症有益.
- 将这种整体模型适应儿科瘤学的独特特征,对于推进治疗结果至关重要.
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