杆菌感染与胆囊和胆道疾病之间的联系:一篇综述
Klay Puay Khim Lim1, Aaron Jia Loong Lee1, Xiuting Jiang1
1Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.
Annals of hepato-biliary-pancreatic surgery
|June 25, 2023
概括
胆囊杆菌 (H. pylori) 感染与胆囊结石和慢性胆囊炎有关,但与胆囊多无关. 需要进一步的研究来确认H. pylori.
科学领域:
- 胃肠病学 胃肠病学
- 肝病学 肝病学是一种肝病学.
- 微生物学 微生物学
背景情况:
- 杆菌 (H. pylori) 是一种与胃潰瘍疾病和胃癌相关的グラム阴性病原体.
- 在各种胆囊和胆道疾病中观察到H. pylori感染,但相关性仍然不清楚.
- 关于H. pylori在胆囊和胆道疾病中的作用,存在文献上的空白.
研究的目的:
- 审查和总结目前关于H. pylori与胆囊和胆道疾病之间的联系的证据.
- 探索H. pylori感染对这些病态的临床管理的影响.
- 解决有关H. pylori在肝胆道疾病中的作用的现有文献缺口.
主要方法:
- 在Medline,PubMed,Embase和Cochrane数据库中进行了全面的文献搜索.
- 检查H. pylori和胆囊/胆道疾病之间的联系的同行评审研究被检索和分析.
- 该审查综合了有关关联,临床影响和进一步研究的发现.
主要成果:
- 杆菌感染与胆病 (胆结石),慢性胆囊炎,胆道癌,原发性硬化胆炎和原发性胆道胆炎有关.
- 在H. pylori感染和胆囊多之间没有发现显著的关联.
- 虽然一些研究表明因果关系,但确的证据需要前性的纵向研究.
结论:
- 胆囊杆菌感染与几种胆囊和胆道疾病有关,不包括胆囊多.
- 需要进行前性研究,以确定H. pylori和胆囊病理之间的确切因果关系.
- 临床医生应考虑H. pylori感染对这些肝胆道疾病患者管理的潜在影响.
相关概念视频
Pathophysiology of Peptic Ulcer Disease: Injurious Factors
646
Peptic ulcers are sores on the stomach's inner lining and the upper small intestine, which are the result of disruptions in the mucosal layer that houses parietal cells which produce gastric acid, and chief cells which secrete pepsinogen.
In the antrum region, G cells secrete the gastrin hormone that binds to gastrin-cholecystokinin-B (CCK2) receptors on parietal and enterochromaffin-like (ECL) cells in the fundic glands. Simultaneously, the vagus nerve releases acetylcholine, which binds...
In the antrum region, G cells secrete the gastrin hormone that binds to gastrin-cholecystokinin-B (CCK2) receptors on parietal and enterochromaffin-like (ECL) cells in the fundic glands. Simultaneously, the vagus nerve releases acetylcholine, which binds...
646
Diseases of the Liver and Gallbladder
674
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
674
Gastritis-II: Pathophysiology
382
Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
382
Peptic Ulcer Disease I: Introduction
215
Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
215
Gallbladder
646
The gallbladder is a small, pear-shaped organ that plays a crucial role in our digestive system. Measuring about 10 cm in length, it is comparable in size to a kiwi fruit and is located in a hollow area on the lower surface of the liver. The gallbladder's primary function is to store and concentrate bile, a fluid produced by the liver that aids in digestion.
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins...
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins...
646
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies
159
Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
159


