身体活动与患有2型糖尿病的老年人认知衰退速度较慢有关
Y Rabinowitz1, R Ravona-Springer, A Heymann
1Yaacov Rabinowitz, Israel, Akiva 22, Ra'anana, Israel, 972-54-5421240, yaacovtr@gmail.com, ORCID ID: https://orcid.org/0000-0003-2642-7304.
The journal of prevention of Alzheimer's disease
|June 25, 2023
概括
维持2型糖尿病 (T2d) 的老年人身体活动与较慢的认知衰退有关. 积极的生活方式显著减缓了全球认知,执行功能和注意力/工作记忆的下降.
科学领域:
- 老年学是一门学科.
- 神经学 神经学
- 内分泌学 在内分泌学.
背景情况:
- 2型糖尿病 (T2d) 是痴呆症和认知衰退的已知危险因素.
- 身体活动与老年人群的认知衰退速度较慢有关.
- 身体活动对T2d老年人认知健康的影响仍未得到充分研究.
研究的目的:
- 调查身体活动水平与诊断为T2d的老年人认知能力下降的速度之间的关联.
- 为了确定身体活跃的生活方式是否能在这个特定的人群中提供对认知障碍的保护.
主要方法:
- 一项前性纵向研究 (以色列糖尿病和认知衰退 - IDCD研究) 追踪了1213名65岁以上的认知正常成年人T2d.
- 使用明尼苏达州休时间活动问卷来评估体育活动.
- 用全面的神经心理学电池评估认知功能,并使用线性混合效应模型分析数据.
主要成果:
- 与"非活跃"组相比,被归类为"活跃" (从事娱乐性体育活动) 的参与者在全球认知 (p=0.005),执行功能 (p=.014) 和注意力/工作记忆 (p=.01) 中的下降速度明显较慢.
- 两组之间没有观察到语义分类或情节性记忆下降的显著差异.
- 由于样本规模较小,不活动的人 (n=19) 被排除在比较分析之外.
结论:
- 身体活跃的生活方式与T2d的老年人保持认知功能有关.
- 促进体育活动可能是一个可行的策略,可以延迟或预防这种高风险人群中痴呆的发病.
- 需要进一步的研究来证实这些发现,并探索干预策略.
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