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儿童急性胰腺炎的长期随访和结果:一个多中心研究
Burcu Volkan1, Bilge Şahin Akkelle1, Nevzat Aykut Bayrak2
1Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Marmara University Faculty of Medicine, İstanbul, Turkey.
Turkish archives of pediatrics
|June 26, 2023
概括
儿童急性胰腺炎的入院人数正在上升,但住院时间较短. 建议对有风险因素的儿童进行早期遗传检测和成像,以防止慢性胰腺炎的进展.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 胰腺学 胰腺学
- 临床流行病学临床流行病学
背景情况:
- 全球急性胰腺炎的发病率正在增加.
- 儿童急性复发性胰腺炎和慢性胰腺炎的进展模式仍未充分记录.
- 了解儿科胰腺炎的进展对于及时干预至关重要.
研究的目的:
- 为了划分儿童胰腺炎的时间变化.
- 分析急性胰腺炎向急性复发性胰腺炎和儿童慢性胰腺炎的进展.
- 为了确定与胰腺炎进展相关的风险因素.
主要方法:
- 多中心回顾性研究.
- 包括在2010年至2017年期间因急性胰腺炎住院的165名儿科患者.
- 对临床特征和疾病进展的审查.
主要成果:
- 在研究期间观察到急性胰腺炎入院率增加.
- 由于急性胰腺炎而减少住院时间.
- 近三分之二的病例自发解决;30.9%的急性复发性胰腺炎和4.3%的慢性胰腺炎. 27.4%的急性复发性胰腺炎病例进展为慢性胰腺炎.
- 13.3%的患者出现了局部并发症.
结论:
- 儿童急性胰腺炎的确诊发病率上升,住院时间缩短.
- 胰腺胆道异常和遗传因素显著增加了进展风险.
- 建议儿童胰腺炎患者早期进行基因检测和放射性成像.
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