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结晶结构主要蛋白质酶的SARS-CoV-2变体结合佐醇基抑制剂

Jiqing Luo1, Weiwei Wang2, Haihai Jiang3

  • 1College of Pharmaceutical Sciences, Gannan Medical University, Ganzhou 341000, China.

Acta biochimica et biophysica Sinica
|June 26, 2023
PubMed
概括

针对SARS-CoV-2的主要蛋白酶 (M pro) 的佐醇抑制剂显示出对变种的承诺. 晶体结构显示YH-53与Mpro突变体形成共价键,有助于更广泛的抗病毒药物开发.

关键词:
这就是SARS-CoV-2病毒.对于YH-53来说,这是一个非常好的选择.班佐提亚 (benzothiazole) 是一种一种抑制剂抑制剂的使用主要蛋白质酶的主要蛋白质酶变种 变种 变种 变种 变种

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