在不同非洲裔人口中,子宫内膜癌风险和趋势
Heidy N Medina1, Frank J Penedo2,3, Clarisse Joachim4
1Department of Public Health Sciences, University of Miami School of Medicine, Miami, Florida, USA.
Cancer
|June 26, 2023
概括
在全球范围内,黑人女性的子宫内膜癌 (EC) 风险不同. 加勒比黑人妇女的EC率较低,但在所有受研究的人群中,侵略性的非子宫内膜组织EC正在增加.
科学领域:
- 妇科瘤学 妇科瘤学
- 流行病学 流行病学
- 癌症研究 癌症研究
背景情况:
- 子宫内膜癌 (EC) 不成比例地影响美国的黑人女性,特别是具有攻击性的亚型.
- 对不同全球人口进行比较分析对于了解非洲裔妇女的EC脆弱性至关重要.
研究的目的:
- 为了比较美国 (佛罗里达州) 和加勒比海 (马丁尼克,瓜德罗普) 的黑人妇女的子宫内膜癌 (EC) 发病率和趋势.
- 调查欧洲共同体风险差异是否与社会环境因素或祖先有关.
主要方法:
- 从佛罗里达州,马丁尼克和瓜德罗普 (2005-2018) 的基于人口的癌症登记处分析了34,789例子宫内膜癌 (EC) 病例.
- 估计非西班牙裔黑人 (NHB) 和非西班牙裔白人 (NHW) 的人口年均百分比变化 (APC) 的年龄调整发病率,发病率比率 (IRR) 和年均百分比变化,使用NHW作为参考.
主要成果:
- 加勒比黑人妇女的子宫内膜体和非子宫内膜体EC亚型的发病率最低.
- 美国 (佛罗里达州) 的NHB女性的非子宫内膜异位细胞的发病率最高 (9.2/100,000),是NHW女性的2.6倍.
- 虽然在美国NHB和NHW人口中,子宫内膜异位结合率每年增加,但在加勒比黑人妇女中没有观察到显著变化. 在所有研究的人群中,非内分泌体EC率显示出日益增长的趋势.
结论:
- 在加勒比黑人妇女中,侵略性非子宫内膜体EC的发病率较低,这表明这种差异可能不仅仅是与祖先有关的问题.
- 在所有人群中,非子宫内膜异位细胞发病率的持续上升趋势需要进一步的流行病学和病因学调查.
关键词:
非洲血统的非洲人.黑色 黑色 黑色在加勒比海加勒比海加勒比海加勒比海.白色 白色 白色 白色 白色 白色这是子宫内膜癌的癌症.这种子宫内膜异位体是什么?发生率的发生率.非内分泌体的二氧化物.基于人口的基于人口的.登记处的注册表可以看到.更多相关视频
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