从2018年至2021年期间的全国数据库中,在 Okayama 的抗菌素耐药性的当前流行情况
Shinnosuke Fukushima1, Hideharu Hagiya1, Kazuhiro Uda2
1Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences.
Acta medica Okayama
|June 26, 2023
概括
抗菌素耐药性 (AMR) 是一个越来越令人担忧的问题. 这项研究发现,日本 Okayama 的 AMR 病原体发病率高于其他县,强调了紧急的感染控制和管理需求.
科学领域:
- 医学微生物学 医学微生物学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 抗菌素耐药性 (AMR) 构成了全球健康的重大威胁.
- 多学科的方法对于有效的抗药性管理至关重要.
- 了解区域AMR病原体的流行率对于有针对性的干预至关重要.
研究的目的:
- 评估和提高人们对日本高水平AMR病原体患病率的认识.
- 将AMR病原体隔离比例在各县进行比较,重点是 Okayama.
- 为了识别特定的AMR病原体,在Okayama有显著的流行.
主要方法:
- 关于七个关键的AMR病原体的数据是从日本鼻感染监测 (2018-2021) 中收集的.
- 病原体包括耐美洛的Pseudomonas aeruginosa,耐甲的黄金葡萄球菌,耐万科米辛的Enterococcus faecium,以及抗埃舍里希亚大肠杆菌和Klebsiella pneumoniae的抗菌株.
- 在 Okayama 和其他日本县之间比较了隔离比例.
主要成果:
- 与全国平均水平相比, Okayama 在所有七种研究的抗药性耐药性病原体的平均隔离比例都高.
- 耐美罗胺的P. aeruginosa (19.9%) 和耐LevOfloxacin的E. coli (49.9%) 在Okayama特别高的流行率.
- 耐甲林的金黄色细菌 (57.2%),耐胺的大肠杆菌 (37.8%) 和耐勒沃素的肺炎细菌 (8.7%) 也在Okayama有显著的流行.
结论:
- Okayama 展示了关键抗微生物耐药性病原体的特别高的流行率.
- 在 Okayama,急需加强感染预防和控制措施.
- 促进抗微生物药物管理和教育医疗保健专业人员对于打击该地区的抗菌耐药性至关重要.
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