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Basophil Activation Test for Allergy Diagnosis
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在老年人群中AIT的临床结果
1Clinical Department of Internal Diseases, Dermatology and Allergology, Medical University of Silesia, Katowice, Poland.
Current opinion in allergy and clinical immunology
|June 26, 2023
概括
过敏原免疫疗法 (AIT) 对60岁以上的吸入物过敏患者是有效和安全的. 语言下免疫疗法 (SLIT) 和注射免疫疗法 (SCIT) 在老年人中都提供持续的临床益处.
科学领域:
- 过敏和免疫学 过敏和免疫学
- 老年医学 老年医学
背景情况:
- 在老年人群中,免疫球蛋白E (IgE) 介导过敏的认识越来越多.
- 20世纪90年代的历史试验证明了吸入过敏原的脱敏化潜力.
研究的目的:
- 对60岁以上吸入物过敏患者的过敏原免疫疗法 (AIT) 疗效和安全性的当前知识进行审查.
- 评估AIT在老年人中的长期影响和安全性.
主要方法:
- 对60岁及以上患者的AIT现有文献和临床试验的审查.
- 对过敏性鼻炎的语言下免疫疗法 (SLIT) 和皮下免疫疗法 (SCIT) 的数据分析.
主要成果:
- 证据证实了AIT (SLIT和SCIT) 对60岁以上患者过敏性鼻炎的有效性.
- 艾特已经证明对特定过敏原的有效性,包括草,树和室内灰尘虫.
- 长期监测表明,AIT在老年人群中具有很高的安全性.
结论:
- 没有禁忌的老年人可以从过敏性鼻炎或喘的AIT中受益.
- 即使在停止AIT治疗后,也可以实现持续的临床改善.
- 当过敏原被准确识别时,注射和舌下注射的两种方式都是有效的.
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