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技术说明:T2和T2*的准确性和精度与渐变回声旋转回声 (GESE) 序列用于心脏成像
Qi Huang1,2, Jason Mendes1, Ganesh Adluru1,2
1Utah Center for Advanced Imaging Research (UCAIR), Department of Radiology and Imaging Sciences, University of Utah, Salt Lake City, Utah, USA.
Medical physics
|June 26, 2023
概括
这项研究优化了梯度回声旋转回声 (GESE) 方法,以快速估计心脏中的T2和T2*. 具有五个回声平面成像 (EPI) 读数的GESE序列在信号与噪声比 (SNR) 充足时,对于心肌T2和T2*映射是有效的.
科学领域:
- 心血管磁共振成像 - 心血管磁共振成像
- 量化MRI技术 量化MRI技术
- 心肌组织的特征鉴定
背景情况:
- 梯度回声旋转回声 (GESE) 方法可以在心脏中快速估计T2和T2*.
- 获取参数对T2和T2*偏差和精度的影响需要进一步调查.
研究的目的:
- 调查影响T2和T2*量化的因素,使用GESE与回声平面成像 (EPI) 读数.
- 为了优化心脏应用的缩小视野中的GESE获取.
主要方法:
- 实现了GESE,可减少视野和外部音量抑制 (OVS),以实现更快的多回声EPI读数.
- 使用克拉默-拉奥下界 (CRLB) 和蒙特卡洛模拟优化了EPI读数的数量.
- 评估了信号与噪声比率 (SNR) 的要求,并比较了健康受试者的OVS方法.
主要成果:
- 通过五个EPI读数实现了最佳GESE性能,特别是在第二和第三读数之间的重定位脉冲中.
- 更高的T2/T2*比率需要增加SNR的目标偏差 (<1毫秒) 和标准偏差 (<5毫秒).
- 3T的最低SNR要求在6到20之间,取决于心肌T2/T2*值;OVS方法的结果与临床参考结果相似.
结论:
- 带有五个EPI读数的GESE序列是一种可行且高效的方法,用于隔膜心肌中T2和T2*估计.
- 如果达到足够的SNR,可以在一心跳内实现心脏T2和T2*映射.
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