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Updated: Jul 25, 2025

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers
10:28

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers

Published on: September 20, 2018

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减少细胞内紧张和细胞粘附促进开放的染色质结构,并增强细胞重编程

Jennifer Soto1, Yang Song1, Yifan Wu1

  • 1Department of Bioengineering, University of California, Los Angeles, CA, 90095, USA.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|June 26, 2023
PubMed
概括

减少细胞粘附和细胞骨张力通过改变表观遗传标记来增强诱导的神经元重编程. 这表明机械线索调节细胞命运的决定,并为细胞重编程提供了新的策略.

关键词:
细胞粘附 细胞粘附细胞骨架 细胞骨架直接重新编程是直接的重编程.表观遗传状态表观遗传状态

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