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Updated: Jul 25, 2025

Synthesis and Evaluation of a Ruthenium-based Mitochondrial Calcium Uptake Inhibitor
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Published on: October 26, 2017

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复合物有助于核准和选择性杀死瘤细胞

Yu Lu1,2, Di Zhu1,2, Liujia Chan3

  • 1Department of Medicinal Chemistry, College of Pharmaceutical Sciences of Capital Medical University, Beijing 100069, P. R. China. wangyuji@ccmu.edu.cn.

Nanoscale
|June 26, 2023
PubMed
概括

像NBD-Ru这样的鲁复合体显示出提高了瘤向和杀死能力. 这种新的基于金属的药物通过转移素受体有效地向癌细胞,穿透细胞核,并减少全身毒性.

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