植物性饮食模式和肺癌死亡率:一个透视性队列研究
Qian Wang1, Qi Cui2, Jin-Ping Gao3
1Department of Oncology, Shengjing Hospital of China Medical University, Shenyang, China.
Food & function
|June 26, 2023
概括
健康的植物性饮食可能会降低肺癌死亡率. 在一项对408名患者的研究中,坚持高健康植物性饮食指数 (hPDI) 得分与肺癌死亡率降低有关.
科学领域:
- 在瘤学瘤学.
- 营养科学 营养科学
- 流行病学 流行病学
背景情况:
- 对于癌症幸存者来说,建议采用植物性饮食.
- 关于植物性饮食对肺癌死亡率的影响的证据有限.
研究的目的:
- 评估植物性饮食模式与肺癌死亡率之间的关联.
- 评估总体,健康和不健康的植物性饮食指数对肺癌存活率的影响.
主要方法:
- 408名新诊断的肺癌患者 (18-79岁) 被纳入.
- 通过111项食物频率问卷 (FFQ) 评估饮食摄入量.
- 考克斯比例危险回归模型用于分析生存数据和饮食指数 (PDI,hPDI,UPDI).
主要成果:
- 在40.97个月的中位数随访期间发生了240例肺癌死亡.
- 较高的健康植物性饮食指数 (hPDI) 得分显示与肺癌死亡率有相反的关联 (Q4 vs Q1:HR 0.66;95% CI 0.45-0.97).
- 每增加10个单位的hPDI与肺癌死亡率降低的风险有关 (HR 0.75;95% CI 0.57-0.99).
结论:
- 坚持高健康植物性饮食指数 (hPDI) 的饮食可能会降低肺癌死亡率.
- 在总体 (PDI) 或不健康 (uPDI) 植物性饮食指数和肺癌死亡率之间没有发现显著的关联.
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