Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

A Benchmark of Modern Statistical Phasing Methods.

bioRxiv : the preprint server for biology·2026
Same author

Practical utility of sequence-to-omics models for improving the reproducibility of genetic fine-mapping.

bioRxiv : the preprint server for biology·2026
Same author

Seq-Scope-eXpanded: spatial omics beyond optical resolution.

Nature communications·2026
Same author

Engineering multiferroism through localized hole doping in a flat-band ferroelectric HfO<sub>2</sub>.

Journal of physics. Condensed matter : an Institute of Physics journal·2026
Same author

Correction to "Iron-Catalyzed Borylation of Aryl Trifluoromethoxides".

Organic letters·2025
Same author

The developing tendon and enthesis are hypoxic and rely on hypoxia-inducible factor 1a (<i>Hif1a</i>) during postnatal development.

bioRxiv : the preprint server for biology·2025
Same journal

Heart-Specific Spinal and Vagal Afferents: Transcriptomic Signatures and Optogenetically Modulated Functional Coupling With Cardiomyocytes.

Comprehensive Physiology·2026
Same journal

The Adipose-Organ Communication Network in Clinical Obesity: From Adiposopathy to Systemic Metabolic Failure.

Comprehensive Physiology·2026
Same journal

Insight Into the Biological Link Between Novel Adiposity Indices and Incident Heart Failure.

Comprehensive Physiology·2026
Same journal

Domino Effect of the Kynurenine Pathway: Systemic Homeostasis, Metabolic Crosstalk, and Therapeutic Potential.

Comprehensive Physiology·2026
Same journal

Lung Pericytes: Molecular Mechanisms, Signaling Pathways, and Roles in Pulmonary Diseases.

Comprehensive Physiology·2026
Same journal

Sleep Disturbances and Male Reproductive Dysfunction: Pathophysiological Mechanisms Linking Obstructive Sleep Apnea and Sleep Deprivation.

Comprehensive Physiology·2026
查看所有相关文章

相关实验视频

Updated: Jul 25, 2025

Author Spotlight: Integrating Single-Cell Transcriptomics with Organoid Cultures for Advanced Research and Therapeutic Insights
08:23

Author Spotlight: Integrating Single-Cell Transcriptomics with Organoid Cultures for Advanced Research and Therapeutic Insights

Published on: June 28, 2024

841

空间单细胞技术用于探索胃肠组织转录基因组.

Hyun Min Kang1, Jun Hee Lee2

  • 1Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA.

Comprehensive Physiology
|June 26, 2023
PubMed
概括
此摘要是机器生成的。

空间转录学提供了一种强大的新方法来了解胃肠道系统. 这些先进的技术揭示了整个肠道组织的基因表达,增强了我们对消化系统生理学的知识.

更多相关视频

Spatial Profiling of Protein and RNA Expression in Tissue: An Approach to Fine-Tune Virtual Microdissection
09:19

Spatial Profiling of Protein and RNA Expression in Tissue: An Approach to Fine-Tune Virtual Microdissection

Published on: July 6, 2022

5.0K
Author Spotlight: Isolating and Analyzing Intestinal Cells of Zebrafish Larvae for Investigating Transcriptomic Aspects of Gastrointestinal Development
06:36

Author Spotlight: Isolating and Analyzing Intestinal Cells of Zebrafish Larvae for Investigating Transcriptomic Aspects of Gastrointestinal Development

Published on: November 10, 2023

1.9K

相关实验视频

Last Updated: Jul 25, 2025

Author Spotlight: Integrating Single-Cell Transcriptomics with Organoid Cultures for Advanced Research and Therapeutic Insights
08:23

Author Spotlight: Integrating Single-Cell Transcriptomics with Organoid Cultures for Advanced Research and Therapeutic Insights

Published on: June 28, 2024

841
Spatial Profiling of Protein and RNA Expression in Tissue: An Approach to Fine-Tune Virtual Microdissection
09:19

Spatial Profiling of Protein and RNA Expression in Tissue: An Approach to Fine-Tune Virtual Microdissection

Published on: July 6, 2022

5.0K
Author Spotlight: Isolating and Analyzing Intestinal Cells of Zebrafish Larvae for Investigating Transcriptomic Aspects of Gastrointestinal Development
06:36

Author Spotlight: Isolating and Analyzing Intestinal Cells of Zebrafish Larvae for Investigating Transcriptomic Aspects of Gastrointestinal Development

Published on: November 10, 2023

1.9K

科学领域:

  • 生理学 生理学 生理学
  • 分子生物学分子生物学
  • 基因组学就是基因组学.

背景情况:

  • 胃肠道 (GI) 组织结构对于分泌,吸收和运动等生理功能至关重要.
  • 胃肠道组织内的异质细胞群体在消化和调节方面发挥着不同的作用.
  • 传统方法在提供基因表达在位的全基因组视图方面存在局限性.

研究的目的:

  • 总结一下空间转录学近期的进展.
  • 讨论这些技术在理解胃肠道生理学的应用.
  • 要突出空间转录学如何阐明肠道组织结构的分子构成.

主要方法:

  • 审查最近的空间转录学技术.
  • 分析基因表达是如何在单个细胞和组织层之间绘制的.
  • 空间转录学数据与胃肠道生理学的整合.

主要成果:

  • 空间转录组学为GI组织中的基因表达提供了全基因组的概述.
  • 这些技术可以详细分析GI层内细胞类型特异性的功能.
  • 空间转录学方面的进步显著提高了对肠道肠道分子结构的理解.

结论:

  • 空间转录学代表了GI研究的重大进步.
  • 这些方法为分子层面的胃肠道生理学提供了前所未有的见解.
  • 空间转录学的应用将进一步提高我们对肠道组织功能和调节的理解.