相关实验视频

Updated: Jul 25, 2025

A Bright NIR-II Fluorescence Probe for Vascular and Tumor Imaging

A Bright NIR-II Fluorescence Probe for Vascular and Tumor Imaging

Published on: March 17, 2023

一个基于氨酸的NIR光探头用于Bi3+和潜在的应用

Pranati Somkuwar¹, R Bhaskar¹, Selva Kumar Ramasamy²

¹Department of Chemistry, School of Advanced Sciences, Vellore Institute of Technology, Vellore-632014, Tamil Nadu, India.

Journal of fluorescence

|June 26, 2023

概括

一种新型的氨酸探针 (P) 可选择性地检测高灵敏度的高 bismuth 离子 (Bi3+),使得水样中的色度和性分析成为可能. 这个探测器提供了一种新的方法来检测 bismuth.

科学领域:

分析化学分析化学
材料科学材料科学材料科学
生物化学生物化学

背景情况:

在环境监测和生物研究中,对金属离子的选择性和敏感检测至关重要.
石离子 (Bi3+) 在各种工业应用和生物过程中发挥作用,需要可靠的检测方法.
现有的Bi³⁺检测方法往往缺乏选择性或灵敏性,导致需要新型探针.

研究的目的:

开发和描述一种新的基于氨酸的探针 (P),用于选择性和敏感地检测Bi3+离子.
研究探头P与Bi3+的光物理性质和结合机制.
评估探针P在现实世界样品中的定量Bi³⁺确定中的适用性,并评估其生物相容性.

主要方法:

使用NMR,IR和ESI-MS.5,10,15,20-Tetrakis(4-hydroxyphenyl) 氨酸 (P) 的合成和表征.
在DMSO:H₂O (8:2,v/v) 介质中进行光谱光度和光谱度研究,以评估光物理性质和选择性.
乔布的情节分析,斯特恩-沃尔默火研究,以及DFT计算,以阐明结合的固态度和机制.

主要成果:

探测器P在Bi³⁺离子的存在下表现出选择性的红色光火,对其他金属离子没有显著的反应.
在探针P和Bi3+之间确定了1:1的固体测量结合比,其关联常数为3.4×10M−1.
探测器达到27nM的Bi³⁺的检测极限,并证明了在具有良好的生物相容性的水样中成功的定量确定.

结论:

合成的氨酸探针P在半水性介质中对Bi³⁺检测具有高度选择性和敏感性.
探测器P代表了第一个用于Bi³⁺检测的 reported色度和化探测器.
探测器的有希望的性能和生物相容性表明其在环境和生物监测中的实际应用潜力.

关键词:

比斯穆特 (Bismuth) 是一种天然矿物.测色仪的颜色测量方法 DFT,生物成像技术,生物成像技术测仪的光测量方法氨酸是氨酸中的一种.灭灭灭灭

更多相关视频

IridiumIII Luminescent Probe for Detection of the Malarial Protein Biomarker Histidine Rich Protein-II

IridiumIII Luminescent Probe for Detection of the Malarial Protein Biomarker Histidine Rich Protein-II

Published on: July 7, 2015

Synthesis and Calibration of Phosphorescent Nanoprobes for Oxygen Imaging in Biological Systems

Synthesis and Calibration of Phosphorescent Nanoprobes for Oxygen Imaging in Biological Systems

Published on: March 3, 2010

相关概念视频

Photoluminescence: Applications

Photoluminescence: Applications

Photoluminescence offers a wide range of applications due to its inherent sensitivity and selectivity. This technique allows for both direct and indirect analyses of the analyte. Direct quantitative analysis is possible when the analyte exhibits a favorable quantum yield for fluorescence or phosphorescence. However, an indirect analysis may be feasible if the analyte is not fluorescent or phosphorescent, or if the quantum yield is unfavorable. Indirect methods include reacting the analyte with...

Labeling DNA Probes

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...