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Updated: Jul 25, 2025

Methods of Ex Situ and In Situ Investigations of Structural Transformations: The Case of Crystallization of Metallic Glasses
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通过时间-温度转换了解无形固体分散中核化的效应

Rahul Lalge1, N S Krishna Kumar1, Raj Suryanarayanan1

  • 1Department of Pharmaceutics, College of Pharmacy, University of Minnesota, 9-177 WDH, 308 Harvard Street S.E., Minneapolis, Minnesota 55455, United States.

Molecular pharmaceutics
|June 26, 2023
PubMed
概括

这项研究确定了预防尼菲迪平 (NIF) 无形固体分散 (ASD) 核化的临界冷却速率. 聚烯利 (PVP) 和基烯基甲基纤维素酸盐酸盐 (HPMCAS) 聚合物影响了核化速率,而PVP显示出更强的相互作用.

关键词:
无形固体分散的无形固体分散结晶化 结晶化的过程.药物 - 聚合物相互作用热挤出方式基甲基纤维素酸盐顺酸 (HPMCAS) 是一种尼菲迪平因 (nifedipine) 是一种尼菲迪平因 (nifedipine) 的一种药物.核化的核化.聚乙烯罗利 (PVP) 是一种聚乙烯.时间-温度转换的转换.

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