在氧化氨酸视网膜病变中,未满足的需求和未来的前景
Imran H Yusuf1, Peter Charbel Issa1, Seong Joon Ahn2
1Oxford Eye Hospital and Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom.
Frontiers in medicine
|June 26, 2023
概括
早期检测氧化氨酸视网膜病变对于预防视力丧失至关重要,但仍然具有挑战性. 这篇文章强调了目前的知识差距以及对这种有毒效应的查和研究的未满足需求.
科学领域:
- 眼科医生 眼科 眼科
- 药理学 药理学是指药理学的学科.
- 毒理学 毒理学 毒理学
背景情况:
- 氧化 (HCQ) 治疗可能导致视网膜病变,严重的毒性作用.
- 早期发现HCQ视网膜病变对于预防不可逆转的视力丧失至关重要.
- 目前的查方法在识别早期HCQ视网膜病变时面临挑战.
研究的目的:
- 总结关于氧化氨酸视网膜病变的现有知识差距.
- 确定临床实践和研究中未得到满足的需求.
- 为了指导未来的查和研究方向.
主要方法:
- 一个有前景的文章.
- 文献综述和当前临床实践和研究的综合.
- 识别早期检测和管理中的挑战.
主要成果:
- 在早期检测氧化网膜病变方面仍然存在重大挑战.
- 除了戒毒之外,缺乏成熟的治疗方法.
- 关于最佳查方案和了解疾病机制的知识缺口存在.
结论:
- 需要进一步的研究,以改善早期检测和了解氧化视网膜病变.
- 在临床实践中解决未满足的需求对于更好的患者结果至关重要.
- 这一观点旨在为管理HCQ毒性的未来努力提供信息和指导.
更多相关视频
10:24Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report
Published on: February 12, 2018
10.2K
09:33An Acute Retinal Model for Evaluating Blood Retinal Barrier Breach and Potential Drugs for Treatment
Published on: September 13, 2016
7.2K
相关概念视频
Open Angle Glaucoma: Treatment
481
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
481
Glaucoma: Overview
630
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
630
Angle Closure Glaucoma: Treatment
577
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
577
Nephrotic Syndrome II : Assessment and Medical Management
10
IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document...
10
