概括
日本食品安全委员会 (FSCJ) 评估了使用Rhodobacter sphaeroides生产的食品添加剂Valencene. 关于其生物生产或成分,没有发现任何健康问题.
科学领域:
- 食品安全评估 食品安全评估
- 微生物生物技术 微生物生物技术
- 食品添加剂评价 食品添加剂评价
背景情况:
- 瓦伦是一种使用Rhodobacter sphaeroides 168.8细菌生产的调味剂.
- 日本食品安全委员会 (FSCJ) 负责评估食品添加剂的安全性.
- 重组DNA技术越来越多地用于食品成分的生产.
研究的目的:
- 对食品添加剂瓦伦进行全面的安全评估.
- 为了评估使用Rhodobacter sphaeroides 168用于Valencene生物生产的安全性.
- 确定与插入的基因,蛋白质和其他组件相关的潜在风险.
主要方法:
- 根据申请人提交的文件和已确定的准则进行安全评估.
- 来自插入基因的蛋白质的毒性和过敏性评估.
- 对复合和宿主蛋白残留物的分析.
- 非活性成分的毒理评估和估计摄入量.
主要成果:
- 没有发现与使用重组技术在瓦伦生产中的风险.
- 毒理学发现和非活性成分的估计摄入量没有引起安全问题.
- 安全评估证实,生物生产过程没有对健康造成风险.
结论:
- 联邦证监会的结论是,使用Rhodobacter sphaeroides 168生产的Valencene对人类消费是安全的.
- 对于食品添加剂瓦伦而言,没有人体健康问题被提出.
- 安全性评估支持使用这种生物制造的调味剂.
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