在商业料牛中估计的变异成分,表型特征和牛充血性心力衰竭的遗传评估
Justin W Buchanan1, Lex E Flagel2, Michael D MacNeil1,3,4
1Simplot Livestock Co., Grand View, ID, United States.
Frontiers in genetics
|June 26, 2023
概括
牛充血性心力衰竭 (BCHF) 是一个越来越令人担忧的养场牛. 使用在收获时的心脏分数的遗传选择可以降低死亡率并改善肉牛的心肺健康.
科学领域:
- 动物科学动物科学
- 遗传学 遗传学 是一个
- 兽医医学 兽医医学 兽医医学
背景情况:
- 牛充血性心力衰竭 (BCHF) 正在养场牛群中增加,造成经济损失和福利问题.
- 之前的研究描述了安格斯牛的心脏形态和肺动脉压 (PAP).
- 需要工具来解决各种养场牛品种中与BCHF相关的死亡率的问题.
研究的目的:
- 调查BCHF在商业料场牛中的发病率和遗传基础.
- 为了确定心脏分数和生产特征之间的遗传相关性.
- 评估使用心脏分数用于基因选择以减轻BCHF的可行性.
主要方法:
- 对32,763头牛进行了心脏形态表型测试,并收集了生产数据.
- 低通基因组型为5001个个体估计遗传参数.
- 分析Angus祖先相关性的基因组品种百分比.
主要成果:
- 高心脏得分 (4或5) 的发生率为4.14%,表明存在显著风险.
- 心脏评分与安格斯祖先有积极的相关性.
- 二元心脏得分的遗传率为0.356,表明选择是可行的.
- 在心脏得分和生长/食特征之间发现了中等的积极遗传相关性.
- 与背部脂肪和大理石分数观察到的负遗传相关性.
结论:
- 在收获时使用心脏分数的遗传选择是可行的,以减少BCHF.
- 在遗传评估中实施心脏评分可以改善心肺健康.
- 解决与经济特征的遗传相关性是管理BCHF发病率的关键.
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