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一个罕见的华法林抗性病例和可能的机制探索

Li Zhao1, Zhenguo Zhai2, Pengmei Li1

  • 1Pharmacy Department, China-Japan Friendship Hospital, Beijing, People's Republic of China.

Pharmacogenomics and personalized medicine
|June 26, 2023
PubMed
概括

研究了一名患有深静脉血栓和肺栓塞的患者的华法林耐药性. 基因突变,特别是CYP4F2基因,被确定为患者对华法林治疗反应不佳的潜在原因.

关键词:
在CYP2C9中.在CYP4F2中.GGCXGGCXGGCXGGCXGGCXGGCXGGCXGGCXGGCXGGCXGGCXGGCXGGCXGGCXGGCXGGCXGGCXGGCXGGCXGGCXGGCXGGCXGGCXGGCXGGCXG这就是VKORC1的原因.这是一种抗凝血药物.华法林的血度 华法林的血度华法林耐药性 华法林耐药性

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