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Updated: Jul 25, 2025

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一个AAV囊体增加了条状体的转导,一个ChAT促进体允许选择性的胆固醇神经元转导

Miguel C Santoscoy1,2,3, Paula Espinoza1,2,3, Demitri De La Cruz1,2,3

  • 1Harvard Medical School, Boston, MA, USA.

Molecular therapy. Methods & clinical development
|June 26, 2023
PubMed
概括

基因相关病毒 (AAV) 载体对脑基因疗法有很大的前景. 一个新的囊体,AAV-S,扩大了纹状体中的基因传递,而胆乙转移酶 (ChAT) 促进体则增强了神经元特异性的表达.

关键词:
在 AAV AAV AAV 中.腺相关病毒载体病毒载体大脑大脑大脑的大脑大脑细胞类型特定的促进剂.胆固醇神经元是一种神经元.基因传递 基因传递 基因传递基因治疗的基因疗法条纹体的条纹体.目标基因表达的目标基因表达转导是指一个转导的过程.

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