Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Synthetic Biology02:55

Synthetic Biology

4.9K
Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
Golden rice
Golden rice is a genetically modified...
4.9K
Dehydration Synthesis01:15

Dehydration Synthesis

133.7K
Overview
Dehydration synthesis (also called a condensation reaction) is the chemical process in which two molecules covalently link together to form a new molecule, along with the release of a water molecule. Many physiologically important compounds form by dehydration synthesis reactions, such as complex carbohydrates, proteins, DNA, and RNA.
Synthesis of carbohydrates
Sugar molecules are covalently linked together by dehydration synthesis. During the reaction, the hydroxyl (-OH) group from...
133.7K
ATP and Macromolecule Synthesis01:28

ATP and Macromolecule Synthesis

5.6K
Biological macromolecules are organic compounds, predominantly composed of carbon atoms. The carbon atoms are covalently bonded with hydrogen, oxygen, nitrogen, and other minor elements. There are four major biological macromolecule classes: carbohydrates, lipids, proteins, and nucleic acids.
Most macromolecules are composed of single subunits, or building blocks, called monomers. The monomers combine with each other using covalent bonds to form larger molecules known as polymers.
Conversion of...
5.6K
Olefin Metathesis Polymerization: Acyclic Diene Metathesis (ADMET)00:53

Olefin Metathesis Polymerization: Acyclic Diene Metathesis (ADMET)

2.0K
Acyclic diene metathesis polymerization or ADMET polymerization involves cross-metathesis of terminal dienes, such as 1,8-nonadiene, to give linear unsaturated polymer and ethylene. As ADMET is a reversible process, the formed ethylene gas must be removed from the reaction mixture to complete the polymerization process.
Similar to cross-metathesis, ADMET also involves the formation of metallacyclobutane intermediate by [2+2] cycloaddition of one of the double bonds of a terminal diene with...
2.0K
Step-Growth Polymerization: Overview01:03

Step-Growth Polymerization: Overview

3.5K
Step-growth or condensation polymerization is a stepwise reaction of bi or multifunctional monomers to form long-chain polymers. As all the monomers are reactive, most of the monomers are consumed at the early stages of the reaction to form small chains of reactive oligomers, which then combine to form long polymer chains in the late stages. Hence, the reaction has to proceed for a long time to achieve high molecular weight polymers.
Many natural and synthetic polymers are produced by...
3.5K
C–C Bond Formation: Aldol Condensation Overview01:10

C–C Bond Formation: Aldol Condensation Overview

13.7K
Aldol condensation is an important route in synthetic organic chemistry used to generate a new carbon–carbon bond under basic or acidic conditions. The aldol condensation reaction presented in Figure 1 constitutes an aldol addition reaction followed by the dehydration process.
13.7K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

A unimolecular GLP-1 and FGF21 dual agonist for treatment of metabolic dysfunction-associated steatohepatitis.

Communications medicine·2026
Same author

Integrating theory and machine learning to reveal determinants of plasmid copy number.

Nature communications·2026
Same author

Biomolecular condensates mediate C-N bond formation.

Nature chemical biology·2026
Same author

Origins of the Intrinsic Redox Activity of Biomolecular Condensates.

Journal of the American Chemical Society·2026
Same author

Biomolecular Condensates Power Nitrogen Cycling via Concurrent Redox Activities.

Journal of the American Chemical Society·2026
Same author

Asymmetry in Hydrophobicity Induces Electric Potential in Non-Charged Biomolecular Condensates.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

相关实验视频

Updated: Jul 25, 2025

Author Spotlight: Developing Synthetic Cells from Programmable Amphiphilic DNA Nanostructures
08:02

Author Spotlight: Developing Synthetic Cells from Programmable Amphiphilic DNA Nanostructures

Published on: May 31, 2024

815

工程合成生物分子凝结物.

Yifan Dai1, Lingchong You1, Ashutosh Chilkoti1

  • 1Department of Biomedical Engineering, Duke University, Durham, NC USA.

Nature reviews bioengineering
|June 26, 2023
PubMed
概括

合成生物分子凝聚剂为控制细胞功能提供了新的途径. 这篇评论探讨了如何构建和使用这些工程凝聚物来精确调节细胞.

科学领域:

  • 细胞生物学 细胞生物学
  • 生物化学 生物化学
  • 合成生物学 合成生物学

背景情况:

  • 生物分子凝聚物通过相位分离形成,组织细胞功能.
  • 了解这些凝结物为设计合成版本打开了道路.
  • 合成冷凝剂为细胞控制提供了新的工具.

研究的目的:

  • 审查合成生物分子凝聚物的构造.
  • 解释合成凝结物如何调节细胞功能.
  • 讨论工程冷凝剂的应用和未来方向.

主要方法:

  • 审查阶段分离驱动冷凝物形成的基本原则.
  • 分析生物分子凝聚物的结构功能关系.
  • 检查可编程合成冷凝剂的设计策略.

主要成果:

  • 生物分子组件可以被设计为驱动相位分离.
  • 凝结物的特性可以调整以实现特定的细胞功能.
  • 合成冷凝剂在细胞控制应用中已经证明了其实用性.

结论:

  • 合成生物分子凝聚物代表了细胞工程的强大平台.
关键词:
生物技术是生物技术.本质上是无序的蛋白质.软材料 软材料 软材料合成生物学 合成生物学

更多相关视频

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
09:34

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Published on: February 6, 2020

7.3K
Synthesis of an Intein-mediated Artificial Protein Hydrogel
15:06

Synthesis of an Intein-mediated Artificial Protein Hydrogel

Published on: January 27, 2014

12.2K

相关实验视频

Last Updated: Jul 25, 2025

Author Spotlight: Developing Synthetic Cells from Programmable Amphiphilic DNA Nanostructures
08:02

Author Spotlight: Developing Synthetic Cells from Programmable Amphiphilic DNA Nanostructures

Published on: May 31, 2024

815
Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
09:34

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Published on: February 6, 2020

7.3K
Synthesis of an Intein-mediated Artificial Protein Hydrogel
15:06

Synthesis of an Intein-mediated Artificial Protein Hydrogel

Published on: January 27, 2014

12.2K
  • 对设计考虑的进一步研究将扩大它们的应用.
  • 工程冷凝剂对先进的细胞调节和生物技术具有前途.