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双边胸部细胞减少手术用于尾起源的形膜瘤

Sanket Mehta¹, Praveen Kammar¹, Vivek Sukumar¹

¹Department of Surgical Oncology, Saifee Hospital, Maharshi Karve Road, Charni Road East, Mumbai, 400004 India.

Indian journal of surgical oncology

|June 26, 2023

概括

肺部扩散的Pseudomyxoma peritonei (PMP) 可以通过胸部细胞减少手术 (CRS) 来治疗. 本案例研究表明,双侧胸部CRS可以在PMP患者中实现长期生存和生活质量.

科学领域:

在瘤学瘤学.
手术瘤学手术瘤学
胸部外科手术胸部外科手术

背景情况:

伪肌瘤周周 (PMP) 中的多发性扩散不常见 (<10%),通常通过胸部细胞减小手术 (CRS) +/-高热性胸内化疗 (HITOC) 进行管理.
手术干预的目的是缓解症状和控制疾病,包括多切除术,皮层切除术和肺切除术.
文献主要报道了用CRS治疗的单边胸部扩散.

研究的目的:

报告一个双边胸部PMP病例,用阶段性胸部CRS治疗.
评估在PMP患者中积极胸部CRS的有效性和安全性.
突出使用多模式CRS延长生存和改善生活质量的潜力.

主要方法:

患者接受了完全的腹部CRS和高温腹腔内化学疗法 (HIPEC) 治疗PMP.
随后,由于有症状的双侧多病,进行了双边分阶段胸部CRS.
在胸部手术期间没有进行高热性胸内化疗 (HITOC).

主要成果:

这两种胸部CRS手术均完成,没有出现重大并发症或发病率.
患者在初始腹部CRS后84个月和胸部CRS后60个月保持无疾病.
该疗法成功管理了症状性胸部疾病,并控制了PMP的进展.

结论:

积极的胸部CRS是PMP患者的可行选择,双边的肺部扩散,即使在广泛的腹部治疗后.
多种模式的CRS,包括胸部干预,可以显著延长选择的PMP患者的存活时间和维持生活质量.
根据疾病生物学和外科专业知识进行仔细的患者选择对于复杂的PMP病例的成功结果至关重要.

关键词:

细胞还原性手术是指细胞还原性手术.头 - - 一个头.腹PMP是多发性的一种.伪瘤 (Pseudomyxoma peritonei) 是一种可能导致瘤的疾病.胸部PMP的使用方法胸腔细胞还原性手术是什么

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