透皮药物治疗对精神分裂症患者焦虑症状的影响
Cuifang Zhu1,2, Xin-Yue Wang1, Jing Zhao1,2
1Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Frontiers in neuroscience
|June 26, 2023
概括
通过皮肤传递药物治疗显著改善了精神分裂症患者的焦虑症状. 这种治疗方法表明了安全的特征,在研究期间没有观察到任何显著的不良影响.
科学领域:
- 精神病学是一个精神病学.
- 药理学 药理学是指药理学的学科.
- 传统中国医药 传统中国医药
背景情况:
- 精神分裂症往往伴随着并发性焦虑障碍,影响患者的治疗结果.
- 通过皮肤递送药物提供了药物管理的潜在替代途径.
研究的目的:
- 评估通过皮肤递送药物治疗治疗治疗精神分裂症患者焦虑症状的疗效和安全性.
主要方法:
- 80名患有焦虑症的精神分裂症患者被随机分配到治疗组 (标准抗精神病药物 + 透皮疗法) 和对照组.
- 汉密尔顿焦虑量表 (HAMA),汉密尔顿抑郁量表 (HAMD-17) 和治疗突发症状量表 (TESS) 用于评估.
- 积极和消极症状量表 (PANSS) 也被管理.
主要成果:
- 与对照组相比,治疗组在3周和6周显示出明显较低的HAMA分数 (p < 0.001).
- 两组之间在HAMD-17,PANSS得分或不良影响方面没有发现显著差异.
- 在治疗组中,疾病持续时间和焦虑症状改善之间发现了负相关性.
结论:
- 通过皮肤递送药物治疗,结合标准治疗,有效地减少精神分裂症患者的焦虑症状.
- 该疗法耐受性良好,并提供了安全的治疗选择.
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