在儿科吉兰 - 巴雷综合征的交感皮肤反应 (SSR)
Mei Jin1,2, Jing Liu1, Kang Liu1,2
1The Children Hospital of Hebei Province, Shijiazhuang, Hebei, China.
Frontiers in neurology
|June 26, 2023
概括
同情性皮肤反应 (SSR) 有助于早期诊断和预后在儿童吉-巴雷综合征 (GBS) 与自主功能障碍 (AD). 在GBS患者中异常的SSR表明潜在的严重程度,并有助于短期预后评估.
科学领域:
- 神经学 神经学
- 儿科 儿科 儿科
- 自主神经系统的自主神经系统
背景情况:
- 吉兰-巴雷综合征 (GBS) 是一种罕见的神经疾病,影响儿童.
- 自主功能障碍 (AD) 是儿科GBS的一个常见并发症.
- 早期诊断和预后评估对于治疗儿科GBS至关重要.
研究的目的:
- 研究患有GBS的儿童的同情性皮肤反应 (SSR) 特性.
- 评估SSR对儿科GBS早期诊断和预后评估的有用性,特别是当AD复杂时.
主要方法:
- 一项前性研究涉及25名患有GBS的儿童和30名健康对照 (HC).
- 在GBS患者和HC患者之间比较SSR发现.
- 对GBS患者的SSR和神经传导研究 (NCS) 结果的分析,将其与临床特征和AD相关联.
主要成果:
- 66.7%的GBS患者患有AD; 72%的人表现出异常的SSR.
- 异常的SSR与GBS显著相关 (P<0.05) 并发生在所有预后不佳的儿科GBS患者中.
- 在康复阶段,SSR和NCS显示出显著的差异 (P = 0.003),在AIDP亚型中存在异常的SSR流行.
结论:
- 自主功能障碍影响三分之二的儿童与GBS.
- 在儿童GBS中,SSR是早期诊断,随访和评估疾病严重程度和短期预后的宝贵工具.
- SSR可以帮助识别预后不佳的患者.
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