文章主题: 由于感染和抗菌治疗而导致的神经病变
Andrés M De León1, Rocio Garcia-Santibanez1, Taylor B Harrison2
1Neuromuscular Division Department of Neurology, Emory University, Executive Park 12 NE, GA 30329 Atlanta, USA.
Current treatment options in neurology
|June 26, 2023
概括
本综述详细介绍了传染性多神经病 (PN) 的原因,重点关注的是免疫反应,而不是直接的神经损伤. 它根据临床表现对神经病变进行分类,以更好地诊断和管理这些具有挑战性的疾病.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 免疫学 免疫学 免疫学
背景情况:
- 多神经病 (PN) 可能是由于各种感染引起的,通常是通过免疫系统激活间接引起的.
- 虽然一些与感染相关的PNS正在减少,但感染和吉兰-巴雷综合征 (GBS) 变体之间的联系越来越被认可.
- 与艾滋病毒治疗相关的神经病变的发生率有所减少.
研究的目的:
- 审查特定感染中的多神经病的表现,诊断和管理.
- 根据临床表型对传染性神经病变进行分类,以改善临床指导.
- 总结与抗微生物药物使用相关的有毒神经病变.
主要方法:
- 关于多神经病的传染性原因的文献综述.
- 基于临床表型的神经病变的分类:大纤维和小纤维PN,GBS,多重单核炎和自主神经病变.
- 包括常见和罕见的感染病因.
主要成果:
- 大多数与感染相关的PNS是由间接的免疫激活引起的,尽管直接的神经或施万细胞感染和毒素产生也会发生.
- 传染性神经病变是由表型 (例如,GBS,自主神经病变) 而不是仅由传染病原体分组.
- 与抗菌素相关的有毒神经病变也被简要地涵盖.
结论:
- 了解传染性多神经病的多种机制对于有效的临床管理至关重要.
- 基于表型的分类有助于临床医生诊断和治疗传染性神经病变.
- 需要继续进行研究,以解决感染相关神经系统疾病的不断变化的局面.
关键词:
自主神经病变是一种自主性神经病变.吉兰·巴雷综合征 (Guillain-Barre综合征) 是一种与艾滋病毒相关的遥远感官多神经病变.汉森氏病是汉森氏病的一种疾病.血管性神经病变是一种神经病变.更多相关视频
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