从慢性病患者的现实世界测量中预测住院治疗:一项原则证明研究
Kate Lyden1,2, Nikita Abraham3, Robert Boucher3
1Department of Kinesiology, University of Massachusetts, Amherst, MA, USA.
Digital health
|June 26, 2023
概括
现实世界的身体行为指标,如每日步数和最佳6分钟步数 (B6SC),与临床测试相关,并预测慢性病 (CKD) 患者的未来住院情况.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 老年学是一门学科.
- 数字健康数字健康
背景情况:
- 慢性病 (CKD) 影响身体功能和运动能力.
- 传统的临床评估可能无法完全捕捉现实世界的身体行为.
- 预测CKD的住院风险对于患者管理至关重要.
研究的目的:
- 评估临床体力功能测量与CKD患者现实世界的身体行为/运动努力之间的关联.
- 确定这些措施是否预测了患有CKD的人未来住院的情况.
主要方法:
- 一项涉及106名CKD参与者的二次分析 (平均年龄69岁).
- 现实世界测量 (最佳6分钟步数 - B6SC,步数/天) 来自动图传感器.
- 与临床6分钟步行测试 (6MWT) 的比较;在2年内收集的住院数据.
主要成果:
- 6MWT和现实世界措施 (B6SC,步骤/天) 都显示出住院风险的良好分离.
- 调整后的考克斯回归显示了显著的关联:6MWT (HR=0.54) 和B6SC (HR=0.70) 预测了更低的住院风险.
- 步骤/天也表明了减少住院风险的趋势 (HR=0.69).
结论:
- 数字健康技术使得CKD患者的身体行为能够远程连续监测.
- 现实世界中的移动性努力措施有效地区分住院风险.
- 这些数字工具为远程管理CKD患者提供了有价值的方法.
更多相关视频
07:31Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack
Published on: May 15, 2020
7.1K
05:15Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
Published on: June 10, 2025
138
相关概念视频
01:28Chronic Kidney Disease III: Interprofessional Care
48
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
48
01:25Chronic Kidney Disease I: Introduction
43
Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage kidney disease (ESKD). At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate...
43
01:30Acute Kidney Injury IV: Diagnostic Studies and Prevention
40
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
40
01:18Chronic Kidney Disease IV: Nursing Management
29
Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of...
29
01:17Factors Affecting Renal Clearance: Renal Impairment
123
Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
123
01:22Acute Kidney Injury I: Introduction
38
Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
38