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腰部校正的BMI预测了基于人口的观察队列研究中发生的糖尿病
Nana Wang1, Yuying Li2, Chuanji Guo3
1Endocrinology Department, Shengjing Hospital of China Medical University, Shenyang, China.
腰部校正的体重指数 (wBMI) 显示出糖尿病 (DM) 的更强的预测能力,而不是传统的措施,如BMI或腰围单独. 这种新的指标,即wBMI,提供了改进的糖尿病风险评估,特别是对于女性.
科学领域:
- 内分泌学 在内分泌学.
- 代谢健康 代谢健康
- 公共卫生 公共卫生
背景情况:
- 腰部纠正的体重指数 (wBMI) 是身体质量指数 (BMI) 和腰围 (WC) 的组合.
- 在肥胖预测方面,wBMI优于单独的BMI或WC.
- 在此之前,wBMI 尚未被用于预测糖尿病 (DM).
研究的目的:
- 评估wBMI对事件DM的预测能力.
- 为了比较wBMI的预测性能与WC,BMI和腰与身高比率 (WHtR).
主要方法:
- 这是一项为期5年的前性队列研究,涉及来自中国西北部的159,000多名参与者.
- 诊断DM是主要的终点.
- 统计分析包括生存分析和C指数比较,以获得预测准确度.
主要成果:
- 较高的wBMI四分位数显著与男性和女性的DM发病率增加有关.
- wBMI,WC,BMI和WHtR都是DM的独立预测因素.
- wBMI表现出最高的预测能力,这在两种性别中都显示出最高的C指数,特别是在女性中.
结论:
- 与WC,BMI和WHtR相比,wBMI是发生DM的优越预测因素.
- 这些发现支持使用wBMI进行增强的DM风险评估.
- wBMI对未来对代谢疾病的研究有潜力.
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