在贝利诺斯塔特治疗和对多重复发性/耐药性血管免疫细胞T细胞淋巴瘤的全原干细胞移植后,完整的血液学反应:一个病例报告
Vincent Camus1, Pascaline Etancelin2, Fanny Drieux3
1Department of Hematology Centre Henri Becquerel Rouen France.
Clinical case reports
|June 26, 2023
概括
贝利诺斯塔特在治疗复发性/耐药性外围T细胞淋巴瘤方面表现有前途. 一名患者在贝利诺斯塔特治疗和干细胞移植后,在两年多时间内实现了持久的完整反应.
科学领域:
- 血液学 血液学 血液学
- 在瘤学瘤学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 周围T细胞淋巴瘤 (PTCL) 是一种具有不良预后的侵袭性血液性恶性瘤.
- 对复发/耐药PTCL的有效治疗选择仍然有限.
研究的目的:
- 突出贝利诺斯塔特在治疗复发/耐药PTCL中的潜在疗效.
- 通过使用贝利诺斯塔特成功治疗复杂PTCL亚型的案例.
主要方法:
- 一份病例报告详细介绍了一名年轻患者的治疗过程,该患者患有重度预治疗,复发/不耐药的结节卵泡辅助T细胞淋巴瘤 (血管免疫芽细胞类型[nTFHL-AI]).
- 患者接受了贝利诺斯塔特治疗,随后进行了全原干细胞移植.
主要成果:
- 贝利诺斯塔特治疗诱导了患者的完整血液学反应.
- 获得的完整反应在治疗后持续了两年多.
结论:
- 贝利诺斯塔特证明了作为复发/耐药PTCL患者的治疗选择的潜力.
- 这一案例支持使用贝利诺斯塔特与干细胞移植结合用于挑战性PTCL病例.
更多相关视频
11:55Induction of Alloantigen-specific Anergy in Human Peripheral Blood Mononuclear Cells by Alloantigen Stimulation with Co-stimulatory Signal Blockade
Published on: March 14, 2011
14.7K
05:32In Vivo Osteo-organoid Approach for Harvesting Therapeutic Hematopoietic Stem/Progenitor Cells
Published on: February 16, 2024
487
相关概念视频
Bone Marrow Sampling and Transplants
363
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
363
Stem Cell Therapy for Tissue Regeneration
4.1K
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
4.1K
