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在患有多微生物血流感染的患者中微生物学分析和死亡风险因素

Junhong Xu¹, Youhua Yuan¹, Baoya Wang¹

¹Department of Clinical Laboratory, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, and People's Hospital of Henan University, Zhengzhou, Henan, 450003, People's Republic of China.

Infection and drug resistance

|June 26, 2023

概括

多微生物血流感染在重症患者中很常见,通常涉及多种耐药细菌. 集中治疗室入院,休克和中枢神经系统疾病是关键的死亡风险因素,需要仔细选择抗生素和减少侵入性手术.

科学领域:

传染性疾病传染性疾病
临床微生物学临床微生物学
关键护理医学关键护理医学

背景情况:

多微生物血流感染 (PBSI) 在临床环境中带来了重大挑战.
确定病因特征和预后风险因素对于患者管理至关重要.

研究的目的:

调查影响PBSI患者结果的原因和危险因素.
确定PBSI患者死亡的独立风险因素.

主要方法:

一项对2021年入院河南省人民医院的141名PBSI患者的回顾性研究.
收集的数据包括实验室索引,入院部门,人口统计,ICU停留和程序.
使用单变量和多变量分析来确定死亡风险因素.

主要成果:

凝聚酶阴性葡萄球菌和Klebsiella pneumoniae分别是最常见的阳性和阴性细菌.
观察到高发病率的甲基西林耐药凝结酶阴性葡萄球菌 (75%) 和耐卡巴胺的K. pneumoniae (45.7%).
确定的独立死亡风险因素包括ICU入院,休克,电解质障碍和中枢神经系统疾病. 患有抗卡巴烯姆PBSI的患者的生存率较低.

结论:

患有PBSI的患者往往病情危急,并感染了多抗药生物体.
监测传染性菌群,明智使用抗生素,并尽量减少侵入性手术对于降低死亡率至关重要.

关键词:

临床特征临床特征病因病因学病因学重症监护病房的重症监护病房是一个重症监护病房.多微生物感染血流感染有关风险因素的风险因素.

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