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胎儿上心脏脂肪厚度:其作为妊娠期糖尿病患者标记物的作用
Amandeep Singh1, Amitojveer S Josan1, Kamlesh Gupta1
1Department of Radiodiagnosis and Imaging, Sri Guru Ram Das Institute of Medical Sciences and Research, Vallah, Punjab, India.
The Indian journal of radiology & imaging
|June 26, 2023
概括
胎儿心上脂肪厚度 (EFT) 在妊娠期糖尿病 (GDM) 的怀孕中显著更高. 测量胎儿EFT显示高灵敏度和特异性作为GDM的新查标记.
科学领域:
- 产科和妇科 产科和妇科
- 胎儿医学 胎儿医学
- 内分泌学 在内分泌学.
背景情况:
- 关于胎儿表心脂肪厚度 (EFT) 和妊娠糖尿病 (GDM) 之间的关联存在有限的研究.
- 孕期糖尿病对母亲和胎儿都有风险.
- 早期查和诊断GDM对于最佳妊娠结果至关重要.
研究的目的:
- 调查胎儿心表脂肪厚度 (EFT) 作为妊娠糖尿病 (GDM) 的潜在查标志物.
- 评估胎儿EFT在怀孕期间识别GDM的诊断性能.
主要方法:
- 一项涉及24至28周孕期孕妇的横截面研究.
- 使用产前超声波测量胎儿心上脂肪厚度 (EFT).
- 诊断为GDM的组与没有GDM的对照组之间的EFT比较.
主要成果:
- 与对照组相比,患有GDM的母亲的胎儿的胎儿胎儿表心脂肪厚度 (EFT) 显著增加.
- 增加的胎儿EFT与2小时口服葡萄糖耐受性测试 (OGTT) 血清葡萄糖水平呈正相关性.
- 接收器操作特征 (ROC) 曲线分析表明,对于胎儿EFT作为GDM预测器的高灵敏度 (96.67%) 和特异性 (90%).
结论:
- 胎儿心上脂肪厚度 (EFT) 是孕期糖尿病 (GDM) 的母亲胎儿显著升高的标志物.
- 尽管平均差异很小,胎儿EFT作为GDM的预测指标具有统计学意义.
- 测量胎儿EFT为查妊娠糖尿病提供了一种新且有效的方法.
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