基于二极管和基于潜力的ECGI方法的早期心室收缩节拍局部化与临床数据的比较
Yesim Serinagaoglu Dogrusoz1,2, Nika Rasoolzadeh1,2, Beata Ondrusova3,4
1Department of Electrical-Electronics Engineering, Middle East Technical University, Ankara, Türkiye.
Frontiers in physiology
|June 26, 2023
概括
与基于潜力的模型相比,基于二极管的源模型提供了更稳定和更强大的早期心室收缩 (PVC) 起源的局部化,用于射频废除指导. 干不均性对每个模型的定位准确性产生不同的影响.
科学领域:
- 生物医学工程 生物医学工程
- 计算电生理学 计算电生理学
- 医疗成像医学成像
背景情况:
- 准确地定位过早心室收缩 (PVC) 的起源对于指导射频切除 (RFA) 至关重要.
- 非侵入性心电成像 (ECGI) 方法面临挑战,原因是源和前模型的变化.
- 干不均性对PVC原产地定位准确性的影响仍然是一个研究领域.
研究的目的:
- 为了比较基于双极和基于潜力的源模型的性能,以定位节奏和自发的PVC起源.
- 评估干不均质对这些定位模型准确性的影响.
- 评估ECGI用于RFA指南的反向方法的稳定性.
主要方法:
- 使用公开可用的电生理学 (EP) 溶液数据 (EDGAR) 对节奏PVC和布拉迪斯拉瓦数据对自发PVC.
- 采用均和不均的干模型来模拟与表心和内心源相关的前置问题.
- 在真实和估计的定位点/PVC来源之间评估的定位错误 (LE).
主要成果:
- 基于双极的模型显示,节奏PVC的中位数LE为25.2mm,自发PVC的中位数LE为30.2-33.0mm.
- 基于潜在的模型给出了步态PVC的中位数LE为13.9mm,自发PVC的中位数LE为28.9-39.2mm.
- 干不均性对基于二极管的解决方案的影响最小,但在心室表面改善了基于潜在的解决方案.
结论:
- 与基于潜力的模型相比,基于二极管的源模型在PVC来源定位方面表现出更高的稳定性和稳定性.
- 干不均性在不同来源模型中不同影响PVC原产地定位的性能.
- 患者特定的几何和前模型需要根据所选择的ECGI源模型表示进行仔细考虑.
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