相关实验视频
Updated: Jul 25, 2025

04:44
Developing a Rat Model for Bipolar Disorder
Published on: May 2, 2025
364
在重新开始治疗后,双极性1型患者的外皮拉米德症状:一个病例报告
Godwin I Orji1, Maria Mansoor2, Sophia B Bellegarde2
1Psychiatry, Interfaith Medical Center, New York, USA.
Cureus
|June 26, 2023
概括
这份案例报告强调,碳酸即使在长期使用后,也可能引起超金字塔症状,例如运动障碍. 临床医生应该监测患者是否有这些罕见的神经学副作用.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 双极性障碍的管理往往涉及情绪稳定剂,如碳酸.
- 患者不遵守长期情绪稳定剂治疗是一个常见的挑战.
- 虽然很少见,但治疗的副作用是已知的.
研究的目的:
- 在重新启动碳酸治疗的患者中报告一个新出现的额外金字塔症状病例.
- 强调认识到EPS作为的潜在不良影响的重要性,无论治疗持续时间如何.
- 提高临床医生对患者神经症状的差异诊断的认识.
主要方法:
- 病例报告详细介绍患者的临床表现和病史.
- 审查患者对碳酸重新开始治疗的反应.
- 神经系统症状的记录,包括硬和不安.
主要成果:
- 患者在重新开始碳酸治疗后不久出现了额外皮拉米德症状,特别是上肢硬和不安.
- 这些神经症状发生,尽管有先前的暴露和不遵守的历史.
- 介绍强调了对疗法的罕见但显著的不良反应.
结论:
- 在接受碳酸治疗的患者中,即使在重新开始服用药物时,也可能出现extrapyramidal症状.
- 临床医生必须在患有运动障碍的患者中保持对诱导的EPS的高度怀疑指数.
- 早期识别和管理EPS对于患者的安全和双相情感障碍治疗的坚持至关重要.
相关概念视频
Mania and Antimanic Drugs: Overview
253
Mania, a psychological condition characterized by elevated mood, increased energy, and reduced sleep need, is part of the bipolar disorder cycle. The exact cause of mania isn't entirely known, but it is thought to be a combination of genetic, environmental, and neurological factors. Bipolar disorder involves alternating manic and depressive episodes. Mood stabilizers like lithium, antipsychotics, and anticonvulsants help manage these episodes. Lithium carbonate is particularly effective as...
253
Bipolar Disorder
109
Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.
109
Psychosis: Goals of Pharmacotherapy
171
Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
171
Psychosis and Antipsychotic Drugs: Overview
348
The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic...
348
Antiepileptic Drugs: Potassium Channel Activators
217
Ezocgabine or retigabine, an antiepileptic drug of remarkable efficacy, has revolutionized the management of seizures. It is a potassium channel activator, explicitly targeting the family of Q subtype potassium channels. It enhances the transmembrane potassium currents, regulating neuronal excitability. This action stabilizes the resting membrane potential, a pivotal factor in mitigating the hyperexcitability that characterizes epilepsy.
Ezogabine has gained approval as an adjunctive treatment...
Ezogabine has gained approval as an adjunctive treatment...
217
Electroconvulsive Therapy
75
Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
75

