与慢性血栓栓塞性肺高血压相关的社会成本:利用链接的国家注册表进行的一项研究
Barbro Kjellström1, Hannes Runheim2, Amélie Beaudet3
1Department of Clinical Sciences Lund, Clinical Physiology and Skåne University Hospital Lund University Lund Sweden.
Pulmonary circulation
|June 26, 2023
概括
慢性血栓栓塞性肺高血压 (CTEPH) 在诊断前后都会显著增加由于医疗保健使用和生产力损失而导致的社会成本. 这些成本是由生产力损失和医疗费用所驱动的,突显了CTEPH的经济负担.
科学领域:
- 心脏病学 心脏病学
- 肺部医学 肺部医学
- 卫生经济学 卫生经济学
背景情况:
- 慢性血栓栓塞性肺高血压 (CTEPH) 是肺栓塞后的罕见但严重的结果.
- 与CTEPH相关的社会成本,包括医疗保健资源利用率 (HCRU) 和生产力损失,没有得到充分记录.
- 了解这些成本对于资源分配和患者管理至关重要.
研究的目的:
- 估计CTEPH患者的总社会成本 (直接和间接).
- 为了比较CTEPH诊断前5年和后5年的成本,与匹配的对照组进行比较.
- 分析手术 (PEA) 和非手术 (非PEA) CTEPH 患者组的成本驱动因素.
主要方法:
- 连接瑞典国家数据库以确定CTEPH队列 (n=369) 和匹配的对照组 (n=1845).
- 估计HCRU (住院,门诊,药物使用) 和生产力损失 (病假,残疾养老金) 每名患者每年.
- 将患者分为PEA和非PEA组进行分层,以进行比较成本分析.
主要成果:
- 与对照人群相比,CTEPH诊断前的社会成本是2.1倍,CTEPH诊断后的8.1倍.
- 在PEA和非PEA组诊断之前,生产力损失是主要的成本驱动因素.
- 在诊断后,处方药和住院是PEA组的关键成本驱动因素,而处方药在非PEA组中占主导地位.
结论:
- CTEPH与大量的社会成本有关,包括医疗保健消费和生产力损失.
- 这些经济影响在CTEPH诊断前几年就很明显,并在诊断后持续很长时间.
- 这些发现强调了CTEPH对个人和社会的重大财务负担.
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