在COVID时代脏恶性瘤的阶段迁移:单中心分析
Ankit Gupta1, Abhijit Patil1, Dhruv Patel1
1MPUH, Nadiad, Gujarat India.
Indian journal of surgical oncology
|June 26, 2023
概括
COVID-19大流行影响了脏恶性瘤的治疗,导致COVID时代的患者出现更大的瘤和晚期疾病,与COVID前时期相比. 这种转变很可能是由于例行检查减少的延迟诊断和患者对感染的恐惧.
科学领域:
- 在瘤学瘤学.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 传染性疾病 传染性疾病
背景情况:
- 由于COVID-19大流行 (由SARS-CoV-2引起),人们对脏恶性瘤患者的癌症治疗和感染预防产生了担忧.
- 将癌症护理与COVID-19传播风险平衡为患者和医疗保健提供者带来了重大挑战.
研究的目的:
- 在COVID-19大流行之前和期间,对脏恶性瘤患者的临床和病理参数进行回顾性分析和比较.
- 为了识别 COVID-19 时代所导致的脏恶性瘤的疾病呈现,阶段或等级的任何变化.
主要方法:
- 在两年内对184名脏恶性瘤患者的回顾性分析 (COVID前:2019年3月至2020年2月;COVID:2020年3月至2021年2月).
- 两个时代之间的患者年龄,瘤大小,临床表现,临床阶段,病理阶段,核等级和转移存在的比较.
- 在p值<0.05.05的情况下评估的统计学意义.
主要成果:
- 患者年龄和临床表现在不同时期之间是可比的,尽管在COVID前发生了更多的例行诊断 (p=0.022).
- 在COVID时代,瘤大小显著更大 (7.10±3.83cm与5.84±3.03cm相比,p=0.017).
- 在COVID时代的患者呈现出明显更高的临床阶段 (p=0.041),病理阶段 (p=0.027),核级 (p=0.007) 和转移 (p=0.005).
结论:
- COVID-19大流行导致脏恶性瘤的显著阶段迁移,患者呈现出更先进的疾病.
- 由于COVID-19的恐惧,减少了例行健康检查和患者避开医院可能导致诊断延迟和结果更差.
- 流行病状况明显掩盖了脏恶性瘤的管理和表现,需要适应性医疗保健策略.
相关概念视频
01:16Kidney Transplant III: Nursing Management
41
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
41
01:26Kidney Transplant II: Surgical Procedure
36
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
36
01:11Renal Failure: Dose Adjustments
127
In patients with renal impairment, drugs undergo significant changes in their pharmacokinetics, which require dosage adjustments to ensure safe and effective therapy.
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
127
01:28Kidney Transplant I: Introduction
29
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
29
01:30Acute Kidney Injury IV: Diagnostic Studies and Prevention
40
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
40
01:24Chronic Kidney Disease II: Clinical Manifestations
40
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
40