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Updated: Jul 25, 2025

A Proteoliposome-Based Efflux Assay to Determine Single-molecule Properties of Cl- Channels and Transporters
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化物抗载体CLCN7是FIG4和VAC14突变体中溶酶体功能障碍的修饰剂

Xu Cao1, Guy M Lenk1, Vedrana Mikusevic2

  • 1Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, United States of America.

PLoS genetics
|June 26, 2023
PubMed
概括

失去FIG4或VAC14会导致溶酶体疾病. 减少CLCN7化物载体可以缓解这些溶酶体问题,并改善神经功能,提供潜在的治疗点.

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