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血小板库存和使用异组血小板悬浮:为输血服务提供一个具有成本效益的战略

Abdulkerim Yıldız¹, Murat Doğan², Mehmet Yalvaç³

¹Hitit University, Erol Olcok Training and Research Hospital, Department of Hematology, Çorum, Turkiye.

Hematology/oncology and stem cell therapy

|June 26, 2023

概括

实施ABO和Rh不兼容的血小板输血和管理库存减少丢弃的血小板缩物. 这一策略对于面临供应挑战的输血服务至关重要.

科学领域:

血液学血液学血液学
输血医学输血医学
血液银行血液银行

背景情况:

血小板 (PLT) 输血在医院中至关重要,特别是在瘤血液学部门.
血小板缩剂 (PCs) 的供应有限和保质期短,对输血服务 (TSs) 构成挑战.

研究的目的:

评估一项新战略对减少丢弃的血小板度的影响.
评估 ABO 和 Rh 不相容的血小板输血的可行性和安全性.

主要方法:

在第三级转诊医院进行了4年 (2017-2021) 的回顾性研究.
从2020年开始实施PLT库存战略,优先考虑ABO相同输血,然后在必要时进行ABO和Rh不兼容的输血.
每年输血和丢弃的PC的比较.

主要成果:

废弃PC的过期率 (ER) 从2019年的11.1%下降到2020年的4.8%.
2020年,有251个ABO和Rh不相容的PC被输血,没有严重的反应.
与前几年相比,2020年PC使用量显著增加.

结论:

管理血小板库存水平和利用组外的PC可以显著减少PLT浪费.
输血服务必须制定量身定制的策略,以确保足够的PC供应,并尽量减少丢弃.

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