在健康的成年人中使用CandyCollect,一种灵感来自糖果的装置,在家里取唾液样本
Wan-Chen Tu1, Anika M McManamen1, Xiaojing Su1
1Department of Chemistry, University of Washington, Seattle, Washington 98195, United States.
Analytical chemistry
|June 26, 2023
概括
糖果Collect设备,一个新的lollipop灵感的唾液收集器,显示100%的一致性检测细菌,如突变性 estreptococcus和金黄色葡萄球菌. 这个用户友好的工具是用户的首选,并且有一年的保质期,有助于呼吸道感染诊断.
科学领域:
- 微生物学 微生物学
- 医疗器械开发 医疗器械开发
- 诊断检测试验 诊断检测试验
背景情况:
- 呼吸道感染在儿童中很普遍,需要改进诊断样本采集方法.
- 目前的唾液采集技术可能是繁的,影响患者的遵守和样品质量.
研究的目的:
- 为了评估CandyCollect设备的有效性和用户偏好,CandyCollect是一款以糖为灵感的新型唾液收集器,用于细菌检测.
- 评估CandyCollect设备与收集唾液细菌的传统口腔抹布和唾液管的一致性.
- 为了确定CandyCollect设备的保质期,用于实际的临床应用.
主要方法:
- 一项全国性的远程研究,涉及健康的成年人使用CandyCollect设备,口腔抹布和唾液管.
- 参与者在家里自行收集样本,完成可用性调查,并返回样本用于qPCR分析.
- 进行了 *Streptococcus mutans* 和 *Staphylococcus aureus* 的细菌检测.
主要成果:
- 糖果收集装置显示100%的一致性与传统方法 (n=14) 的阳性细菌检测结果.
- 参与者将CandyCollect设备列为他们最喜欢的采样方法 (26名参与者).
- 该设备在室温下保持长达一年的稳定性.
结论:
- 糖果收集器是一个用户友好和有效的工具,用于收集唾液细菌.
- 高用户偏好和长期保质期支持其在临床诊断和远程医疗中的潜在整合.
- 这种新的采集方法可以改善用于呼吸道感染诊断的样本采集.
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