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免疫规避的结构演变决定性形状病原体宿主热带性宿主热带性

Ashley L Marcinkiewicz1, Kalvis Brangulis2,3, Alan P Dupuis1

  • 1New York State Department of Health, Division of Infectious Diseases, Wadsworth Center, Albany, NY 12208.

Proceedings of the National Academy of Sciences of the United States of America
|June 26, 2023
PubMed
概括

在Borrelia burgdorferi外表面蛋白CspZ中微小的变异通过改变补充因子H结合来驱动宿主热带. 这种蛋白质图案调节了细菌在不同储库宿主中的感染性和传播,揭示了病原体适应的进化机制.

关键词:
在CspZ中.莱姆病是莱姆病的一种疾病.补充补充补充补充补充补充补充.这就是H因子H因子.主体热带主义 主体热带主义

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