怀孕妇女甲状腺体积的参考值和预测因素
Lisette Leal Curí1,2, María de Las Mercedes Rubén Quesada3,4, Daysi Antonia Navarro Despaigne3,2
1Universidad de Ciencias Médicas de La Habana, Cuba, lealcurilisette@gmail.com.
Archives of endocrinology and metabolism
|June 26, 2023
概括
这项研究确定了孕妇甲状腺体积的参考值,发现自由三甲状腺素和甘油三可以预测变化. 这些发现对于怀孕期间监测甲状腺健康至关重要.
科学领域:
- 内分泌学 在内分泌学.
- 产科 产科 产科 产科 产科
- 公共卫生 公共卫生
背景情况:
- 由于临床和生化因素,甲状腺体体积在人群中波动,怀孕显著影响这些变化.
- 在怀孕期间确定甲状腺体积的精确参考值对于准确的临床评估至关重要.
研究的目的:
- 为了确定孕妇甲状腺体积的参考值.
- 确定预测怀孕期间甲状腺体积的临床和生化因素.
主要方法:
- 一项涉及360名健康孕妇的横截面研究.
- 收集关于母亲年龄,妊娠年龄,吸烟,BMI,甲状腺激素和其他生化标志物的数据.
- 使用超声波测量甲状腺体积.
主要成果:
- 甲状腺体的平均体积为5.3毫升 (第一季度),5.4毫升 (第二季度) 和5.6毫升 (第三季度).
- 建立了甲状腺体体积的三个月特定的参考间隔.
- 自由三甲状腺素和甘油三被确定为甲状腺体体积的显著预测因子 (经校正的R2 = 0.12,p = 0.000).
结论:
- 这项研究为古巴孕妇的甲状腺体积提供了第一个参考值.
- 确定了甲状腺体体积的关键预测因素,有助于临床监测.
- 强调在孕妇人群中考虑甲状腺功能的重要性,特别是在消除缺乏症疾病的地区.
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